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The addition of genetic risk variant data to conventional childhood risk factors improves risk assessment of impaired fasting glucose and type 2 diabetes in adulthood

Genetic Data Help ID Risk of Future Impaired Fasting Glucose

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Genetic score, clinical risk factors can ID children at high risk for impaired fasting glucose, T2DM
Genetic variants in CYP2C8 and SLCO1B1 impact the therapeutic response to rosiglitazone in patients with type 2 diabetes

CYP2C8, SLCO1B1 Variants Impact Response to Rosiglitazone

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Genetic variants have clinical impact on response to rosiglitazone, but not pioglitazone
Black breast cancer survivors in the United States are less likely than white or Hispanic women to get follow-up genetic screening and surgeries that can help prevent cancer recurrence

ASCO: Follow-Up Care Lacking for Black Women With Breast Cancer

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Genetic testing, risk-reducing surgery more likely for whites, Hispanics
A new study has identified genetic factors in black men with a strong West African ancestry that are associated with a lower risk of central obesity. But this apparent benefit doesn't extend to black women

Genes May Lower Risk of Obesity in Men of West African Descent

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But the effect does not seem to apply to women with the same West African ancestry
A BRCA gene database can help physicians better understand their patients' genetic risk for breast and ovarian cancer

Gene Database Offers Doctors Insights Into Breast, Ovarian CA

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Database includes more than 6,200 BRCA variants
Researchers have identified immune genes that may affect mortality in patients with glioblastoma multiforme

Eight Immune Genes Identified As Playing a Role in Glioblastoma

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Discovery might eventually lead to better treatment for glioblastoma multiforme
Genetic analysis can improve diagnosis and management of intellectual developmental disorder and unexplained metabolic abnormalities

Genetic Analysis Offers Options for Some Developmental Delay

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Exome sequencing led to better treatments in four of 10 cases studied
Women who carry common gene variants linked to breast cancer can still reduce risk of the disease by following a healthy lifestyle

Genetic Breast Cancer Risk Can Be Mediated by Healthy Lifestyle

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Key lifestyle factors include maintaining a healthy weight, not smoking, limiting alcohol, no HRT
Average leucocyte telomere length and the abundance of short telomeres (percent LTL <3 kb) are not significant independent determinants of subclinical atherosclerosis

Telomere Length Not Significantly Associated With Atherosclerosis

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LTL, abundance of short telomeres are not independent determinants of atherosclerosis
Men who experience the loss of chromosome Y from their blood cells as they age may have an increased risk of developing Alzheimer's disease

Loss of Y Chromosome in Blood Tied to Alzheimer’s Risk in Men

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The greater the Y chromosome loss, the higher the risk of developing Alzheimer's, researchers say