Tag: Genetics
ESR1 Mutations Tied to Worse Survival in Metastatic Breast CA
ESR1 mutations prevalent in ER-positive metastatic breast cancer and linked to shorter survival
Targeted Therapies Beneficial in KRAS-Mutated NSCLC
Improved progression-free survival for patients treated with therapy not containing erlotinib
Study IDs Two Novel Loci Linked to Insulin Sensitivity
Associations for BCL2 and FAM19A2 were independent of known cardiometabolic loci
15 Genomic Regions Associated With Depression Identified
Many located near genes involved in brain development
Potential New Asthma Genes ID’d in Genome-Wide Study
Combining GWAS with subsequent lung eQTL analysis revealed disease-associated SNPs
‘Ice Bucket Challenge’ Led to Significant ALS Gene Discovery
Money raised during the campaign helped scientists ID gene linked to amyotrophic lateral sclerosis
Effects of APOE Gene May Be Apparent in Childhood
Findings may lead to earlier interventions, preventive measures for future brain injuries, dementia
Risk Score Could Help ID Alzheimer’s Risk in Young Adults
Score also associated with worse memory, clinical progression in older adults
Genetic Risk Score Impact on BMI Varies Across Birth Cohorts
Larger magnitude of association between genetic risk score for BMI and BMI in later birth cohorts
Elevated Risk of Death for Osteogenesis Imperfecta
Higher risk of death from respiratory diseases, gastrointestinal diseases, and trauma
