Tag: Genetics
Misunderstanding of BRCA Test Results Affects Mastectomy Rates
Half of average-risk patients with variants of uncertain significance may undergo bilateral mastectomy
AACR: Genetic Mutations Seen in Many Childhood Cancer Survivors
One in four children who lived through cancer developed another cancer by age 45, researchers say
ANGPTL3 Deficiency Linked to Reduced CAD Risk
Heterozygous carriers of ANGPTL3 loss-of-function mutations have reductions in TGs, LDL-C
BRCA Mutation Testing Shifts to Unaffected Women
From 2004 to 2014, greater percent of testing in unaffected women versus cancer patients
Genetic Hyperglycemia Raises Risk of Coronary Artery Disease
Increased risk of coronary artery disease is separate from diabetes risk
Off-Label Donepezil Rx for MCI Could Be Risky for Some Patients
Medication has detrimental effect on patients with the K-variant of the butyrylcholinesterase gene
Cost-Effectiveness Compared for Metastatic Melanoma Treatments
First-line pembrolizumab or nivolumab followed by second-line ipilumumab most cost-effective
Gene Therapy Described in a Patient With Sickle Cell Disease
But treatment has only been given to one patient so far
ACOG Recommends Use of Carrier Screening Before Pregnancy
Two Committee Opinions expand guidelines on carrier screening; highlight importance of counseling
Circulating Extracellular RNAs Linked to Insulin Resistance
In age-, sex-, and BMI-adjusted models, 18 ex-RNAs were associated with insulin resistance
