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Plasma suPAR levels independently predict renal function decline in individuals with apolipoprotein L1 risk variants

suPAR Protein Levels Impact CKD Risk With APOL1 Variants

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Risk reduced with lower levels of plasma suPAR, strengthened by higher levels
For patients with acute myeloid leukemia and a FLT3 mutation

Longer Survival for Midostaurin + Chemotherapy in AML With FLT3

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Prolonged overall, event-free survival for patients with acute myeloid leukemia, FLT3 mutation
For patients undergoing outpatient colonoscopy

Family History Questionnaire Ups Genetic Counseling for CRC

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Findings in patients who received family history questionnaire before outpatient colonoscopy
More than half of patients with advanced cancer who undergo tumor genomic profiling are interested in learning their secondary germline findings

Many With Advanced Cancer Want Secondary Germline Findings Info

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Attitudes toward learning influenced by patients' personal disease experience, health status
The presence of clonal hematopoiesis of indeterminate potential is associated with coronary heart disease

Clonal Hematopoiesis Linked to Coronary Heart Disease

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CHIP linked to coronary heart disease, myocardial infarction in humans; atherosclerosis in mice
Angiotensin I-converting enzyme gene rs4343 polymorphism is associated with the risk of migraine

Polymorphism in rs4343 of ACE Gene Linked to Migraine

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Odds ratio of migraine 4.17 for G/G versus A/A, A/G polymorphism in angiotensin I converting enzyme
Breast cancer risk peaks around the 40s for BRCA1 mutation carriers and around the 50s for BRCA2 carriers

Family Hx, Mutation Position Key Variables in BRCA1/2 Cancer Risk

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Study findings provide cancer risk patterns based on BRCA status using prospective data
Regular use of nonsteroidal anti-inflammatory drugs is associated with improved survival among colorectal cancer survivors with KRAS wild-type tumors

NSAID Use, Survival Link Varies With KRAS Status in CRC Patients

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Use of NSAIDs tied to better survival for colorectal cancer survivors with KRAS wild-type tumors
The physical and mental health benefits of pursuits like yoga and meditation begin in the genes

Yoga May Be Able to ‘Reverse’ Stress-Inducing DNA Reactions

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Mind-body interventions lead to decrease in nuclear factor kappa B and cytokines, researchers say
Two new medications that target specific genetic mutations may improve survival for patients with specific types of advanced non-small-cell lung cancer

ASCO: Novel Meds Show Promise in Advanced NSCLC

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Results presented from two phase III trials