Tag: Genetics
Characteristics of Diabetes in Infancy Explored
Overall frequency of diabetic ketoacidosis 66.2 percent; odds increase with age at diagnosis
Sleep-Disordered Breathing Linked to Cognitive Dysfunction
Hypoxemia and sleepiness associated with cognitive deficits, with strongest effect in APOE-ε4 carriers
Genetic Variation Impacts Pharmacokinetics of Exemestane
Significant differences in plasma exemestane area under the curve for OATP1B1 genotype groups
Research Supports Genetic Testing in Early Life Epilepsy
Faster diagnosis leads to faster treatment, researcher says
Gene Expression May Predict Response to Methotrexate in RA
Correlations for p21, caspase 3, and RUNX2 with the change in disease activity score of 28 joints
Case Highlights Polygenic Risk in Severe Hypertriglyceridemia
Patient with hypertriglyceridemia had polymorphisms producing triglyceride risk score of 19
More Genetic Tests May Benefit Ashkenazi Jewish Cancer Patients
For Ashkenazi Jewish women with breast cancer, mutations identified in other genes, including CHEK2
MYCN Copy Number Tied to Poor Features in Neuroblastoma
Patients with MYCN gain had inferior outcomes, including lowest response rate after chemo
Germline Mutations Up in Men With Prostate CA, One Other CA
However, most of these men do not meet current clinical criteria for germline testing
Whole-Genome Sequencing of Uncertain Clinical Utility
Testing may prompt additional clinical actions of unclear value, researchers say
