Tag: Genetics
CYPC19*17 Allele May Influence Response to PPI Treatment
Kids with CYPC19*17 alleles without corresponding loss-of-function alleles have longer times with pH <4
Genotype-Guided Warfarin Dosing Cuts Adverse Events
Risk of composite of major bleeding, INR ≥4, VTE, death down for hip, knee arthroplasty patients
APOE Allele Type Tied to Mortality Risk
No racial difference in the association between these alleles and mortality
Alcohol Aids Cerebellar Deficit From Movement Disorder
Cerebellar networks may play key role in symptom generation in these patients
Histamine May Play Role in Colorectal Tumorigenesis
Histamine-producing probiotic reduces inflammation, suppresses colon tumors in mice
New Link Seen Between Gene Fusion and Bladder Cancer
Previously overlooked section of fusion found to negatively impact cancer cells, researchers say
PD-L1 Mainly Expressed in Metastatic CRC Lesions
Overall, 81.8 percent of metastatic CRCs and 40.9 percent of primary lesions had PD-L1 expression
Mutational Signatures Can More Accurately ID MMR Deficiency
Mutational signatures better report mismatch repair deficiency than sequencing of MMR genes
Genetic Variants Tied to Preterm Birth, Gestational Length
Four loci found to be significantly associated with gestational duration, three with preterm birth
Universal Sequencing of Cancer Genes Ups Mutation Detection
Increased detection of heritable mutations over the predicted yield of testing based on guidelines
