Tag: Genetics
apoE Aggregation May Impact apoE-Mediated Plaque Formation
Anti-human apoE-4 antibody preferentially binds unlipidated aggregated apoE over lipidated version
Complete Genome Sequence Can Be ID’d From Amniotic Fluid
Concordance of variant calls between cellular, cell-free DNA, with parental libraries >96 percent
Vigil Immunotherapy Tolerated Well for Recurrent Ovarian CA Tx
And, PARP 7 protein plays significant role; survival up with genetic mutations, higher expression levels
Fewer SIDS Cases Result From Genetic Heart Disease Causes
Findings may help prevent unnecessary genetic testing of surviving family members
Too Few Early Breast CA Patients Given Formal Genetic Counseling
43.5% of women with early-stage breast cancer with indications for risk evaluation get counseling
Genetic Variations Impacting Empathy Tied to Psych Issues
Positive correlations of genetic variations with Empathy Quotient, risk for schizophrenia, anorexia
Molecular Markers May ID Alzheimer’s Before Clinical Onset
Amyloid-positive PSEN1 E280A mutation carriers have elevated levels of tau deposition before onset
Genetics Should Inform Care in Noncompaction Cardiomyopathy
Genetic status linked to risk of major adverse cardiac events in NCCM patients
Losartan May Improve Endothelial Function in Marfan Syndrome
Therapeutic importance may be increased in endothelial nitric oxide release, not ATR1 inhibition
Multidomain Lifestyle Intervention May Aid Cognition in APOE ε4 Carriers
No significant difference seen in intervention effect between carriers and noncarriers of APOE ε4
