Tag: Genetics
Advanced Prostate Cancer Variant More Common Than Thought
Incidence of tx-emergent small-cell neuroendocrine prostate cancer 17 percent among those with mCRPC
Attending Surgeon Influences Genetic Testing in Breast Cancer
About one-third of surgeon variation explained by patient volume, surgeon attitudes to genetic testing
Patient Interest Fairly High for Melanoma Genetic Risk Testing
Reduced interest seen in minority and less educated populations
High-Risk APOL1 Not Tied to CVD, Stroke in Older Black Women
High-risk APOL1 genotype is linked to HFpEF hospitalization in postmenopausal African-Americans
Organic Solvents + Genetics May Increase Risk of Multiple Sclerosis
Finding of susceptibility seen regardless of smoking status
Ethics of Genealogy Data Use for Solving Crimes Discussed
Ethical discussion relates to issues of informed consent, privacy, and justice
Next-Generation Sequencing May Improve Pediatric Epilepsy Tx
In children with drug-resistant epilepsy, NGS can help establish diagnosis, improve treatment efficacy
Genetic Risk, Lifestyle Predict CVD, Diabetes Independently
No interactions seen for any outcome; log-additive effect on risk of developing cardiovascular disease
ASCO: Endocrine Tx Noninferior for HR+, HER2− Breast Cancer
Similar efficacy for endocrine, chemoendocrine tx for women with midrange 21-gene recurrence score
Worse Survival for BRCA Germline Mutation Carriers in Pancreatic CA
For BRCA germline mutation carriers, better survival seen with platinum-based chemotherapy
