Tag: Genetics
Genetic Mutations May Add to Racial Disparity in Child B-ALL
Increased incidence of IKZF1 deletion and IGH-CRLF2 translocation seen in Hispanic/Latino children with B-ALL
Dementia Risk Up in Men With Genetic Mutation for Hemochromatosis
Male p.C282Y homozygotes have lower T2* measures on brain MRI in areas including the putamen, thalamus, hippocampus
Biomarker May Predict Treatment Outcome in Advanced Melanoma
Changes in plasma levels of ctDNA associated with survival outcomes in BRAF V600 mutation-positive unresectable or metastatic melanoma
Actionable Drug-Gene Interactions Common in U.K. Primary Care
Actionable drug-gene interactions identified in 19.1 to 21.1 percent of all new prescriptions for 56 drugs
Genetic Data Suggest Increases in BP May Cause A-Fib
Causal relationship of BP and a-fib did not change when SNPs associated with possible confounders were excluded
Genes That Best Predict Breast Cancer Risk Identified
And estimates determined for breast cancer risk in association with pathogenic variants in known predisposition genes
EPA, DHA Intake From Fish May Reduce Childhood Asthma Risk
Higher intake at age 7 years linked to lower odds of incident asthma at 11 or 14 years among FADS minor G allele carriers
Causal Link Suggested for Smoking, Subarachnoid Hemorrhage
Genetic susceptibility to smoking, assessed using polygenic risk score, is associated with increased risk for SAH
Autistic Traits ID’d in Carriers of CNVs Linked to Autism
54 percent of carriers of certain copy number variants have elevated levels of autistic traits
Polygenic Risk Scores May Improve IBD Risk Prediction
For every population in BioMe biobank, combining risk scores from distinct ancestral populations improved risk prediction for IBD
