Tag: Genetics

When given more information, almost half of research participants who initially refused opted to accept secondary genetic findings

CoRSIV-based model, with a positive predictive value of 80 percent, surpassed the performance of a model based on polygenic risk score

Mutations in actionable breast cancer risk genes present in 3.2 percent of older women with breast cancer

Polygenic risk scores for bipolar disorder and schizophrenia linked to structure and function of the ventromedial prefrontal cortex

For men and women with high genetic risk, five-year cancer incidence down significantly with a favorable lifestyle

No genetic heart disease-sports-associated mortality seen in 2,056 combined years of follow-up

Polygenic variants tied to similar risk for developing glaucoma as some monogenic variants and are more prevalent in the general population

Families with positive predictive test results had better functioning scores than those with negative predictive test results

Studies involving human genome editing should be made public, even though it would not necessarily stop unprincipled scientists

Findings seen in BRCA1 and BRCA2 mutation carriers; reduction greater with longer duration of use in BRCA1 carriers