Tag: Genetics
Bilateral Salpingo-Oophorectomy Beneficial in BRCA1/2 Carriers With Personal History of Breast Cancer
BSO not associated with increased risk for cardiovascular diseases, ischemic heart disease, or cerebrovascular disease
Early-Life Exposure to Certain Bacteria May Impact Early-Onset Colorectal Cancer Incidence
Countries with higher colorectal cancer incidence rates have higher mutation loads in signatures caused by bacteria-produced mutagen colibactin
Guidelines Developed to Improve Newborn Screening for Cystic Fibrosis
Seven recommendations developed, including use of floating immunoreactive trypsinogen cutoff over fixed cutoff
Circulating Tumor DNA Can ID Outcomes for Patients With Melanoma
ctDNA detection at baseline was associated with worse recurrence-free, overall survival in BRAFV600-mutant stage III melanoma
Link Between Global β-Amyloid, Tau Deposition Varies by Sex
Women and those with paternal history of Alzheimer disease have stronger association between Aβ, tau deposition than men or those with maternal history
Prostate Cancer Screening Program Beneficial in Top Decile of Polygenic Risk Score
Targeted screening to participants in ≥90th percentile of polygenic risk score results in detection of cancer warranting clinical management in 55.1 percent
Minimal TV Viewing May Cut ASCVD Risk in Those With T2DM Genetic Risk
Medium and high T2DM genetic risk not linked to increased risk for ASCVD when TV viewing is no more than one hour/day
Mutational Signatures Tied to Haloalkane Exposure Are Enriched in Firefighters
Researchers say identifying occupational correlates with variants associated with exposure to haloalkanes may help pinpoint avoidable occupational hazards
Ultra-Rapid Molecular-Genetic Assays Feasible for Tumor Classification During Surgery
Ultra-rapid digital droplet PCR can measure the levels of tumor cells in a tissue sample in about 15 minutes
Sisters of Those With Adverse Pregnancy Outcome Also Have Increased CVD Risk
Women with APO and their APO-free sisters both have increased risks relative to unrelated APO-free comparators
