Tag: Genetics
ASCO: ctDNA Analysis Guides Treatment of Stage II Colon Cancer
ctDNA-guided approach to determining the need for adjuvant therapy noninferior to standard management for recurrence-free survival
Height May Impact Risk for Disease
Mendelian randomization phenome-wide association study performed to examine relationship between height and clinical traits
Candidate Biomarkers Identified for Psoriasis Progression
Genomic, proteomic, and metabolomic biomarkers identified from systematic review of relevant studies
Screening Could Help Identify Familial Hypercholesterolemia
For adults aged 20 to 39 years, clinical criteria alone would yield 1.3 cases per 1,000 screened; adding genetic testing would increase the yield to 4.2 cases
Impact of Healthy Lifestyle on GDM Risk Varies With Genetic Risk
Lifestyle intervention effective in reducing age-adjusted occurrence of GDM only among those with the highest genetic risk for type 2 diabetes
Polygenic Risk Score for OA Predicts Risk for Hip, Knee Replacement
Participants with high PRS had increased risk for joint replacement; stronger association seen with hip replacement for women versus men
Genetics, Diet Quality Independently Linked to T2DM Risk
Low diet quality versus high diet quality linked to about 30 percent increase in risk for type 2 diabetes regardless of genetic risk
Shared Genetic Variants for COVID-19 Severity, Medical Conditions ID’d
Other medical conditions have associations with the same genetic variants associated with COVID-19 severity
Development of a Clinical Polygenic Risk Score Assay Described
Physician- and patient-oriented informational materials developed to support decision-making about polygenic risk scores
FDA Warns About Genetic Noninvasive Prenatal Screening Tests
Tests should not be used alone to diagnose fetal chromosomal abnormalities
