Tag: Genetics
Plasma ctDNA Genotyping Can Accelerate Time to Treatment for NSCLC
Median time to treatment was 39 days for ACCELERATE cohort versus 62 days for reference cohort using standard tissue genotyping
Genes Identified in Association With Multiple Sclerosis Severity
Significant association identified with rs10191329 in the DYSF-ZNF638 locus, with risk allele shortening time to needing walking aid
Moderate- to Vigorous-Intensity Physical Activity Cuts Diabetes Risk
Larger absolute risk reduction seen among those with the highest genetic risk
Genetically Adjusted PSA Levels Improve Prediction of Prostate Cancer
Genetically adjusted prostate-specific antigen more predictive of aggressive prostate cancer than unadjusted PSA
ASCO: Germline Testing Underused in Cancer Patients
Rates of testing lower among Asian, Black, and Hispanic patients versus White patients
Genetic Links Seen for HDL Cholesterol, Systolic BP With Alzheimer Disease
Genetically determined high-density lipoprotein cholesterol and systolic blood pressure linked to increased odds of Alzheimer disease
AUA: Genomic Urine Test Accurately Predicts Bladder Cancer
Findings based on a subset of 10 genes with greatest predictive power
Homozygous Familial Hypercholesterolemia Has Variable Presentation
Low-density lipoprotein cholesterol goals achieved by a minority of adults and children despite multiple lipid-lowering treatments
Population Genomic Screening for Three Conditions Likely Cost-Effective
Genomic screening for Lynch syndrome, hereditary breast and ovarian cancer syndrome, and familial hypercholesterolemia likely cost-effective for adults younger than 40 years
Genetically Predicted Rheumatoid Arthritis Linked to Osteoporosis
Positive association was robust when MR Egger, weighted median, weighted mode were exploited
