Tag: Genetics
Childhood Cancer Treatment, Genetics Contribute to Subsequent Neoplasm Risk
Contributions quantified for subsequent neoplasms in childhood cancer survivors
Shorter Leukocyte Telomere Length Linked to Higher Incidence of Age-Related Brain Diseases
Shorter leukocyte telomere length linked to higher incidence rates of stroke, dementia, late-life depression as composite and individually
Mitochondrial Genetics Key to Metastatic Melanoma Immunotherapy Resistance
Patients belonging to haplogroup T exhibit unique nivolumab-resistant baseline peripheral CD8+ T-cell repertoire
Parents Delaying Introduction of Nuts and Eggs, Tied to Increase in Food Allergy Risk
Most highly allergenic foods introduced to infants at 6 to 9 months
Early Dog Exposure May Modify Genetic Effect on Atopic Eczema Risk
Findings support observational epidemiology showing protective effect of dog exposure early in life
Central Adiposity Measures Associated With Psoriasis Risk
Significant interaction seen for full psoriasis polygenic risk score with waist-to-hip ratio on psoriasis risk
ASCO: Encorafenib + Cetuximab + Chemo Lengthens Survival in Metastatic CRC
Significantly longer progression-free and overall survival seen in patients with BRAF V600E mutations
Risk for Postpartum Psychosis Higher When Full Sibling Has Experienced It
Despite increased relative recurrence risk in siblings, overall likelihood of postpartum psychosis remains low
HPV Genome Sequencing Superior in Detecting Head & Neck Cancer
Whole-genome sequencing-based ctHPVDNA detection has highest sensitivity, specificity for HNSCC
Low, High HDL Linked to Risk for Age-Related Macular Degeneration
LPA was identified as a novel single nucleotide polymorphism that is associated with increased risk for AMD