Tag: Genetics
Gene Expression Profile Test IDs Patients Who Can Skip SLNB in Melanoma
Of patients identified as low risk by combined clinicopathological factors and GEP test, only 7.1 percent were SLN-positive
Niraparib Plus AAP Improves Survival in mCSPC With HRR Gene Alterations
Significant improvement in radiographic progression-free survival seen first in BRCA subgroup
Estimates of Breast CA Risk for Pathogenic Variants Vary by Family Hx
Estimates for established pathogenic variants vary by family history and potentially modifiable risk factors
Polygenic Risk Score 313 Can Predict Risk for Breast Cancer After In Situ Disease
Significant association seen for increasing continuous PRS313 and risk for contralateral disease after DCIS
Early Exposure to Dogs May Reduce Risk for Childhood Asthma
No link seen between early exposure to cat allergens and asthma risk
Physical Frailty May Contribute to Risk for Dementia Development
Potential causal relationship seen between physical frailty and dementia in forward MR analysis, but null association seen in reverse MR
Aspirin Linked to Lower CRC Recurrence for Molecularly Defined Subgroup
Significantly lower incidence of colorectal cancer recurrence seen for patients with somatic alterations in PI3K pathway genes
Smoking Tied to Increased Risk for Type 2 Diabetes
People with a genetic susceptibility to developing diabetes may be more vulnerable to the adverse effects of smoking
Exa-Cel Gene Therapy Improves Quality of Life in Severe Sickle Cell Disease
Exa-cel also shows beneficial effects on health-related quality of life for adults and adolescents with transfusion-dependent β-thalassemia
Mediterranean Diet Beneficial in Those With High Alzheimer Disease Risk
Adherence to the Mediterranean diet more effectively modulates dementia-related metabolites in APOE4 homozygotes
