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Tag: Genetics

Childhood Cancer Treatment, Genetics Contribute to Subsequent Neoplasm Risk

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Contributions quantified for subsequent neoplasms in childhood cancer survivors

Shorter Leukocyte Telomere Length Linked to Higher Incidence of Age-Related Brain Diseases

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Shorter leukocyte telomere length linked to higher incidence rates of stroke, dementia, late-life depression as composite and individually

Mitochondrial Genetics Key to Metastatic Melanoma Immunotherapy Resistance

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Patients belonging to haplogroup T exhibit unique nivolumab-resistant baseline peripheral CD8+ T-cell repertoire

Parents Delaying Introduction of Nuts and Eggs, Tied to Increase in Food Allergy Risk

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Most highly allergenic foods introduced to infants at 6 to 9 months

Early Dog Exposure May Modify Genetic Effect on Atopic Eczema Risk

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Findings support observational epidemiology showing protective effect of dog exposure early in life

Central Adiposity Measures Associated With Psoriasis Risk

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Significant interaction seen for full psoriasis polygenic risk score with waist-to-hip ratio on psoriasis risk

ASCO: Encorafenib + Cetuximab + Chemo Lengthens Survival in Metastatic CRC

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Significantly longer progression-free and overall survival seen in patients with BRAF V600E mutations

Risk for Postpartum Psychosis Higher When Full Sibling Has Experienced It

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Despite increased relative recurrence risk in siblings, overall likelihood of postpartum psychosis remains low

HPV Genome Sequencing Superior in Detecting Head & Neck Cancer

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Whole-genome sequencing-based ctHPVDNA detection has highest sensitivity, specificity for HNSCC

Low, High HDL Linked to Risk for Age-Related Macular Degeneration

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LPA was identified as a novel single nucleotide polymorphism that is associated with increased risk for AMD