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Among infants breastfed by mothers who are receiving drug therapy for epilepsy

Antiepileptic Drug Exposure Low in Breastfeeding Infants

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Median percentage of infant-to-mother AED concentration ranged from 0.3 to 44.2 percent
Among patients with tuberous sclerosis complex (TSC)

Purified CBD May Help Treat Drug-Resistant Epilepsy

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Those taking CBD versus placebo had greater reduction in seizures associated with tuberous sclerosis complex
Levetiracetam

Three Meds Equal as Second-Line Therapy for Status Epilepticus

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Levetiracetam, fosphenytoin, valproate treat seizures unresponsive to benzodiazepine in children, adults
Limited evidence suggests that self-management strategies modestly improve some outcomes among persons with epilepsy

Self-Management Strategies Offer Limited Benefit in Epilepsy

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Education-based approaches improve self-management behavior; psychosocial therapy approaches up QoL
Sudden unexpected death in epilepsy can occur across the full spectrum of epilepsies

Sudden Death Can Occur in Full Spectrum of Epilepsies

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Only 37 percent of patients with sudden unexpected death in epilepsy took last dose of antiseizure meds
There is an increased risk for behavioral problems in children of mothers with epilepsy who take common antiepileptic drugs during pregnancy

Prenatal Antiepileptic Rx Exposure Ups Risk for Behavioral Issues

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Findings seen among Dutch children exposed to one of four common antiepileptic drugs in utero
Valproic acid and topiramate are confirmed teratogens

Study Confirms Teratogenicity of Valproic Acid, Topiramate

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Eight specific types of major congenital malformations associated with prenatal exposure to valproic acid
Laser interstitial thermal therapy targeting greater amygdala volume is more likely to be associated with Engel I outcomes for mesial temporal lobe epilepsy

Targeted Laser Surgery Treats Temporal Lobe Epilepsy

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Engel I outcomes more likely with ablations targeting specific lobe structures
Antiepileptic drug use is not significantly associated with dementia risk in patients in Germany

Antiepileptic Drugs Not Tied to Dementia Risk

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No increased overall risk found, but levetiracetam generic brands tied to higher dementia risk
The robotic stereoelectroencephalography procedure to determine whether patients with pharmacoresistant epilepsy are candidates for brain surgery is safer and more efficient and more often leads to favorable epilepsy outcomes than the traditional subdural electrode implantation method among those undergoing resection or ablation

Less Invasive Method Safely IDs Epilepsy Surgical Candidates

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Stereoelectroencephalography has better outcomes than subdural electrode implants in some cases