Tag: Epilepsy
Concentrations of Certain Antiseizure Meds Drop During Pregnancy
Dose-normalized concentrations of lamotrigine, levetiracetam, lacosamide, oxcarbazepine, and zonisamide decreased during pregnancy
Responsive Neurostimulation Tolerated in Pediatric Epilepsy
Further study needed to determine long-term efficacy and safety and optimize patient selection
Genetic Diagnosis May Aid Management of Pediatric Epilepsy
Establishing a genetic diagnosis for patients with unexplained infantile or childhood-onset epilepsy can help individualize treatment
Delay to Diagnosis of Nonmotor Seizures Longer in Youth
Delays tied to more seizures prior to diagnosis, conversion to motor-type seizures, potentially preventable injuries
Whole-Plant Cannabis Effective, Tolerated for Pediatric Epilepsy
86 percent reduction seen in seizure frequency for children with intractable epilepsy, with no significant adverse events
Hypertension May Increase Risk for Late-Onset Epilepsy
After adjustment for prevalent and interim stroke, risk for developing epilepsy increased almost twofold
Oxcarbazepine Tied to Nontrauma Fracture in Children Aged 4 to 13 With Epilepsy
Initiating oxcarbazepine, but not levetiracetam, linked to increased incidence rate ratio for nontrauma fracture
Some Newer Antiseizure Meds May Not Increase Suicide Risk
Current evidence does not support increased suicidality for certain newer antiseizure medications; class warning may not be merited
Cognitive Outcomes Studied for In Utero Exposure to Antiseizure Meds
No significant differences in language development seen at age 2 years for children born to mothers with epilepsy
AAN: Fetal Exposure to Antiseizure Meds Has No Neuropsychological Impact
No difference found in primary outcome of Verbal Index score at age 3 years with fetal exposure to ASM or for those born to healthy women