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Tag: Epilepsy

Concentrations of Certain Antiseizure Meds Drop During Pregnancy

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Dose-normalized concentrations of lamotrigine, levetiracetam, lacosamide, oxcarbazepine, and zonisamide decreased during pregnancy

Responsive Neurostimulation Tolerated in Pediatric Epilepsy

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Further study needed to determine long-term efficacy and safety and optimize patient selection

Genetic Diagnosis May Aid Management of Pediatric Epilepsy

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Establishing a genetic diagnosis for patients with unexplained infantile or childhood-onset epilepsy can help individualize treatment

Delay to Diagnosis of Nonmotor Seizures Longer in Youth

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Delays tied to more seizures prior to diagnosis, conversion to motor-type seizures, potentially preventable injuries

Whole-Plant Cannabis Effective, Tolerated for Pediatric Epilepsy

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86 percent reduction seen in seizure frequency for children with intractable epilepsy, with no significant adverse events

Hypertension May Increase Risk for Late-Onset Epilepsy

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After adjustment for prevalent and interim stroke, risk for developing epilepsy increased almost twofold

Oxcarbazepine Tied to Nontrauma Fracture in Children Aged 4 to 13 With Epilepsy

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Initiating oxcarbazepine, but not levetiracetam, linked to increased incidence rate ratio for nontrauma fracture

Some Newer Antiseizure Meds May Not Increase Suicide Risk

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Current evidence does not support increased suicidality for certain newer antiseizure medications; class warning may not be merited

Cognitive Outcomes Studied for In Utero Exposure to Antiseizure Meds

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No significant differences in language development seen at age 2 years for children born to mothers with epilepsy

AAN: Fetal Exposure to Antiseizure Meds Has No Neuropsychological Impact

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No difference found in primary outcome of Verbal Index score at age 3 years with fetal exposure to ASM or for those born to healthy women