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Two naloxone products used to treat opioid overdose patients remain chemically stable long after their expiration dates

Naloxone Products Stay Effective Long After Expiration Date

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Narcan, Evzio chemically stable for at least 10 to 12 months after listed expiration dates
A bipartisan bill meant to combat the United States' opioid abuse epidemic was signed into law Oct. 24 by President Donald Trump.

Bill to Fight U.S. Opioid Crisis Signed Into Law

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Legislation expands treatment options, removes ban on Medicaid reimbursement at certain facilities
Since at least 1979

Mortality for Unintentional Drug Poisonings Up Since 1979

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Trajectory of overall mortality rate smooth; no exponential trajectories in rates for individual drugs
Medicaid expansion was associated with gains in insurance among low-income adults with substance use disorders

Medicaid Expansion Linked to Gains in Insurance Coverage

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But no corresponding increase in treatment of substance use disorders among low-income adults
From July 2016 to June 2017

Naloxone Rarely Administered by Layperson in Opioid Deaths

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Bystanders present in large proportion of overdose deaths; 17.4 percent involve Rx opioids only
From 2014 to 2017 there was an increase in tianeptine exposure calls reported by poison control centers to the National Poison Data System

CDC: Increase in Tianeptine Exposures From 2014 to 2017

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Most commonly reported health effects were neurologic, cardiovascular, and gastrointestinal
The rate of naloxone administrations by emergency medical services providers increased 75 percent from 2012 to 2016

CDC: EMS Administration of Naloxone Up From 2012 to 2016

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Monitoring non-fatal overdose events from EMS data may aid in developing emergency response
There have been substantial increases in complete abstinence from substance use reported by high school students over the past 40 years

Abstinence Rates for Substance Use Increasing Among Teens

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Trends in non-use differed by substance, with marijuana use decreasing the least
The U.S. Surgeon General released an advisory urging increased availability of the opioid overdose-reversing drug naloxone earlier this year

U.S. Surgeon General Urges More Americans to Carry Naloxone

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More individuals, including family, friends, those personally at risk, urged to carry naloxone
A novel

NIH Initiative Aims to Address Opioid Misuse Over Long Term

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'Helping to End Addiction Long-Term' will focus on goals of improving addiction tx and pain management