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Smoking cigarettes can leave a lasting imprint on human DNA

Smoking Appears to Have Broad, Long-Lasting Impact on DNA

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Changes related to disease found in more than 7,000 genes, though many 'recover' five years after quitting
Detection of circulating tumor DNA after resection of stage II colon cancer may identify patients at increased risk of recurrence

Circulating Tumor DNA May Help Predict Colon CA Recurrence

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Findings in patients after resection of stage II colon cancer
For men with metastatic prostate cancer

DNA-Repair Gene Mutations ID’d in Metastatic Prostate Cancer

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Prevalence of 11.8 percent for germline DNA-repair gene mutations presumed to be deleterious