Tag: DNA-
Blood Biomarker May Detect Acute Heart Transplant Rejection
Blood test measuring percent donor-derived cell-free DNA could eliminate much of the need for endomyocardial biopsy
Methylation Analysis of cfDNA IDs >50 Cancer Types
Sensitivity increased with increasing stage from 39 percent in stage I to 92 percent in stage IV
Low-Dose Chest CT Does Not Seem to Alter Chromosomal DNA
Increase in number of double-strand breaks, chromosomal aberrations seen with standard-dose CT
Fragmentation Profiles of Cell-Free DNA Can Detect Cancer
Combined with mutation-based cell-free DNA analyses, 91 percent of cancer patients identified
Plasma Marker Predicts Allograft Failure in Lung Transplant
Average donor-derived cell-free DNA in highest tertile linked to increased risk for allograft failure
Review Addresses Cell-Free DNA Sequencing in Pregnancy
cfDNA testing for trisomy 21, 18, 13 recommended in pregnancy; no FDA oversight for testing
Diagnostic Mutations ID’d in Chronic Kidney Disease Patients
Whole-exome sequencing identified diagnostic mutations, including PARN mutations, in two patients
Downregulation of miR-126 Augments DNA Damage Response
Reduced miR-126 levels in lungs from mice exposed to cigarette smoke, smokers' lung epithelial cells
Shift Work May Affect the Body’s Ability to Repair DNA Damage
Lower levels of 8-hydroxydeoxyguanosine noted in the urine of those who worked at night
Complete Genome Sequence of Zika Isolated From Semen
Many answers to questions about the virus may lie in the viral genome