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Experimental mood induction changes interleukin-18 levels and is associated with changes in central opioid neurotransmission

Experimental Mood Induction Impacts IL-18 Levels

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Experimental sadness increases IL-18, with changes more pronounced in depressed volunteers
Early childhood depression is associated with cortical gray matter development in late school age and early adolescence

Childhood Depression Tied to Cortical Gray Matter Development

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Alterations in gray matter volume loss, thinning in association with major depressive disorder
For patients with major depressive disorder

CYP2C19 Polymorphisms Impacts Citalopram Metabolism

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CYP2C19*2 polymorphism seems to contribute to interindividual variability in CIT metabolism
Cognitive behavioral therapy and antidepressants could both be equally effective as stand-alone treatments for major depressive disorder

Cognitive Therapy, Meds Equally Effective for Major Depression

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Researchers find both treatments can benefit patients with major depressive disorder
More than one in four doctors-in-training may be depressed

Depression Not Uncommon Among Resident Physicians

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Grueling medical training may help explain finding
Depression is independently associated with increased risk of readmission for acute exacerbation of chronic obstructive pulmonary disease

Depression Ups Readmission Odds for COPD Exacerbation

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Reduced one-year readmission with in-hospital tobacco cessation counseling
For individuals with diabetes

Comorbid Stress, Depressive Symptoms Common in Diabetes

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Increased risk of adverse cardiovascular outcomes with elevated stress and/or depressive symptoms
Light therapy

Bright Light Therapy Might Also Treat Nonseasonal Depression

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Treatment for seasonal affective disorder could have broader application
A new small study is adding evidence to the theory that insulin resistance may play a leading role in some cases of depression. Findings from the study were published online Oct. 12 in Psychiatry Research.

Pioglitazone Found to Help Some With Unremitting Depression

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Insulin resistance may underlie some cases, researchers say
There's little evidence that taking omega-3 fatty acid supplements helps treat depression

Omega-3 Supplements Don’t Help With Depression

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U.K. scientists find little evidence they ease symptoms