Tag: Dementia
Long-Term Gantenerumab May Slow Decline in Dominantly Inherited Alzheimer Disease
Hazard ratio for clinical decline in Clinical Dementia Rating-Sum of Boxes was 0.53 for those treated with gantenerumab the longest
Burden of Alzheimer Disease Rose Worldwide From 1990 to 2021
Additionally, trends show increasing cross-country inequalities, with higher burden in higher sociodemographic index regions
Increasing Sleepiness Linked to Dementia Risk in Oldest Old Women
Individual associations with dementia also seen for sleep efficiency, wake after sleep onset, nap duration, nap frequency
Menopausal Hormone Therapy Linked to Faster Regional Tau Accumulation in Older Women
Hormone therapy has indirect effect on cognitive decline through regional tau accumulation; no links with tau for women younger than 70 years
Music-Based Interventions May Help Short-Term Depression, Behavior With Dementia
Review shows no evidence of long-term effects from music-based therapeutic interventions
Antidepressant Use May Speed Up Cognitive Decline in Patients With Dementia
Associations seen for sertraline, citalopram, escitalopram, and mirtazapine
Long-Term NSAID Use Linked to Reduced Dementia Risk
No association seen for cumulative nonsteroidal anti-inflammatory drug dose with reduced dementia risk
Decline in BMI, Waist Circumference Seen in Decade Before Dementia
Dementia cases had lower BMI and waist circumference and faster declines; HDL levels generally higher predementia
Variability in Total Cholesterol, LDL Cholesterol Linked to Dementia
Higher variability also linked to cognitive impairment with no dementia and with faster decline in global cognition, episodic memory
Intensive BP Control Linked to Long-Term Cognitive Benefits
Rates of both MCI and composite of MCI or probable dementia lower with intensive treatment in extended follow-up study