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Tag: Crohn’s Disease

Small Increase in Lymphoma Risk Seen With Crohn Disease, Ulcerative Colitis

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Hazard ratios highest for patients exposed to immunomodulators and biologics or second-line biologics

Adalimumab + Methotrexate Beneficial for Pediatric Crohn Disease

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Reduction in treatment failure seen for adalimumab, but not infliximab, initiators treated with methotrexate combination therapy

Genetic, Lifestyle Factors Independently Linked to IBD Risk

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For those with high genetic risk, hazard ratios were reduced nearly by half for favorable lifestyle versus unfavorable lifestyle

Perianal Disease, Stricturing or Penetrating Behavior Tied to Crohn Disease Outcomes

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Findings in Brazil similar to those in countries with a high prevalence of Crohn disease

Lifestyle Modification Can Reduce Proportion of IBD Burden

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A considerable proportion of ulcerative colitis, Crohn disease cases could be prevented by adherence to low modifiable risk score, healthy lifestyle

About Half of Patients With IBD Have Zinc Deficiency

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Overall mean zinc deficiency prevalence 54 percent in Crohn disease and 41 percent in ulcerative colitis

C-Section Linked to Increased Risk for Crohn Disease in Offspring

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No association seen between mode of delivery and other gastrointestinal disorders later in life among offspring

Diagnostic Accuracy of MRE Indices Studied for Active Crohn Disease

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High sensitivity, but low specificity, seen for sMARIA, London, 'extended' London scores for active terminal ileal Crohn disease

MRI Index Can Predict Postop Recurrence in Crohn Disease

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In validation cohort, MONITOR index ≥1 had sensitivity of 87 percent, specificity of 75 percent, NPV of 75 percent

FDA Approves Skyrizi for Moderately to Severely Active Crohn Disease

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Skyrizi is first specific interleukin-23 approved to treat Crohn disease