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From February to March 2020

February to March 2020 Saw Surge in Hydroxychloroquine Rx

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Number of patients receiving hydroxychloroquine, chloroquine prescriptions climbed across the U.S.
In a case series of 31 patients

Chilblains in Recent Case Series Not Tied to COVID-19 Infection

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SARS-CoV-2 undetected by PCR on nasopharyngeal swabs and in biopsy samples of skin in 31 patients
Social distancing is one of the main measures to combat COVID-19 spread

Social Distancing Effective for Mitigating COVID-19 Spread

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Decreased mobility correlated strongly with reduced COVID-19 case growth rates across U.S. counties
Patients with COVID-19 appear to have a heightened risk for acute ischemic stroke compared with patients with influenza

Acute Ischemic Stroke Risk Higher With COVID-19 Than Influenza

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Higher risk remains even when adjusting for demographic and clinical features
Vaccine maker Novavax will receive $1.6 billion from the U.S. government to provide 100 million doses of a COVID-19 vaccine by early 2021

Company Gets $1.6 Billion From U.S. Government for COVID-19 Vaccine

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Novavax has never brought a product to market before
Late-stage human trials to assess whether a double antibody cocktail can prevent and treat COVID-19 infection have started

COVID-19 Antibody Cocktail Begins Late-Stage Human Trials

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Trial will assess whether it can prevent infection among uninfected people in close contact with an infected person
Endotheliopathy is present in COVID-19 and is associated with critical illness and death

Endotheliopathy ID’d in COVID-19, Tied to Higher Mortality Risk

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Soluble thrombomodulin concentration >3.26 ng/mL linked to lower rates of hospital discharge, survival
From March 23 to April 23

Incidence of Abusive Head Trauma in Infants May Be Up During Lockdown

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Abusive head trauma cases increased 1,493 percent compared with previous three years
The majority of individuals using an online COVID-19 self-assessment tool report mild or moderate symptoms possibly associated with COVID-19

Most Using Online COVID-19 Tool Report Mild, Moderate Symptoms

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Authors say self-assessment tool could ease burden on the health care system, collect useful information
Persons with HIV hospitalized with COVID-19 have similar outcomes to demographically-matched patients without HIV

Outcomes Similar for COVID-19 in Patients With, Without HIV

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Rate of patients who required mechanical ventilation, died similar for those with HIV, matched comparators