Tag: COPD
FDA Approves Nucala for Chronic Obstructive Pulmonary Disease
Approval is for adult patients with COPD with eosinophilic inflammation
Persistent, New Mucus Plugs Associated With Faster Decline in FEV1 in COPD
The steepest decrease in FEV1 seen for those with persistently positive mucus plugs who resume smoking
Mepolizumab Yields Lower Rate of Moderate/Severe Exacerbations in COPD
Time to first moderate or severe exacerbation longer with mepolizumab in patients with COPD, history of exacerbations, eosinophil count ≥300 cells/µL
Women Have Higher Risk for COPD Than Men, Regardless of Smoking History
Female gender linked to increased chronic obstructive pulmonary disease risk in those with and without a history of smoking
Higher Stress Tied to Worse Respiratory Outcomes With COPD
Platelet activation, oxidative stress may be pathways impacted by increased perceived stress, authors say
Adverse Outcomes Increased With Long-Term Inhaled Corticosteroids in COPD
Significantly greater composite adverse outcome rates seen for long- versus short-term inhaled corticosteroid use for prevalent, inception cohorts
COPD Tied to Increased Risk for Death in Patients With Arthritis
Findings seen for both all-cause and cardiovascular disease mortality
Certain Glucose-Lowering Meds Associated With Lower Risk for COPD Exacerbations
Lower risk for COPD exacerbations seen with SGLT-2 inhibitors and GLP-1 receptor agonists, but not with DPP-4 inhibitors
Injurious Falls Common in Last Years of Life With COPD
Odds for use of fall risk-increasing drugs higher in those with falls versus without
Beginning to Smoke Before Age 15 Increases Risk for COPD
Findings independent of cigarette pack years, current smoking status, secondhand smoke exposure