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Use of a faulty device in a regulatory drug trial has raised questions relating to rivaroxaban use

Safety Issues Raised in Key Trial Supporting Rivaroxaban Use

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Defective point-of-care device used in warfarin arm of ROCKET AF trial calls results into question
For warfarin-treated patients

Carbamazepine Affects Warfarin Anticoagulation

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Carbamazepine co-treatment linked to subtherapeutic anticoagulative effect of warfarin
For healthy subjects

Prednisolone Therapy Induces Procoagulant State

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Ten days of treatment linked to increase in peak thrombin, velocity index, PAI-1, and vWF
Intravenous thrombolysis treatment might benefit stroke patients who needed help with daily living before their stroke

IV Thrombolysis Aids Patients Dependent Before Their Stroke

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Study finds favorable results among older adults who already had health problems
For patients with esophageal cancer

ASCO: VTE Is Risk Factor for Recurrence in Esophageal Cancer

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No significant difference in survival with VTE, but odds of recurrence are increased
In patients with essential thrombocythemia

Splenomegaly Ups Thrombosis in Essential Thrombocythemia

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In multivariate analysis, splenomegaly retained negative prognostic role for thrombosis
New recommendations have been developed for antithrombotic therapy for venous thromboembolism. The Antithrombotic Therapy for VTE Disease: CHEST Guideline was published online Jan. 7 in CHEST.

Recommendations Developed for Antithrombotic Tx in VTE

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Guidelines updated for 12 topics; new recommendations address three new topics
For surgical residents

Feedback to Surgical Residents Improves Use of VTE Prophylaxis

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Improvement in resident performance and significant reduction in harm for patients
The pepducin PZ-128 offers rapid

Pepducin PZ-128 Inhibits Platelet Protease-Activated Receptor-1

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Rapid, specific, dose-dependent, reversible inhibition seen in patients with coronary artery disease
For patients with acute traumatic cervical spinal cord injury

D-Dimer Levels Predict DVT in Cervical Spinal Cord Injury

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Only D-dimer level at two weeks after injury accurately predict deep vein thrombosis formation