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Tag: Cholesterol: Dietary

Low, High HDL Linked to Risk for Age-Related Macular Degeneration

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LPA was identified as a novel single nucleotide polymorphism that is associated with increased risk for AMD

Lipoprotein(a) Levels Tied to Increased Risk of Recurrent Atherosclerotic CVD Events

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Deleterious effect of lipoprotein(a) ≥180 nmol/L possibly mitigated by high-impact LDL-cholesterol-lowering therapy

Combination Lipid-Lowering Therapy Linked to Greater Drop in LDL-C

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Greater reduction seen in LDL-C; reductions also seen in all-cause mortality, major adverse CV events, stroke incidence

Olpasiran Leads to Significant Reduction in Oxidized Phospholipids

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Olpasiran leads to significant and sustained reduction in OxPL on apolipoprotein B

Decline in BMI, Waist Circumference Seen in Decade Before Dementia

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Dementia cases had lower BMI and waist circumference and faster declines; HDL levels generally higher predementia

Elevated HDL Cholesterol Linked to Increased Risk for Glaucoma

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Elevated LDL cholesterol, total cholesterol, triglycerides linked to reduced risk for glaucoma

Variability in Total Cholesterol, LDL Cholesterol Linked to Dementia

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Higher variability also linked to cognitive impairment with no dementia and with faster decline in global cognition, episodic memory

HDL Cholesterol May Protect Against Brain Atrophy

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Association seen between HDL cholesterol and greater grey matter volume in midlife independent of traditional risk factors

Lower Levels of Total Cholesterol Seen in More Recent Birth Cohorts

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More recent cohorts also have lower levels of fasting triglycerides, but higher levels of fasting glucose

AHA: Muvalaplin Reduces Lipoprotein(a) Levels in Individuals With Cardiovascular Risk

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Reduction in levels seen using an intact lipoprotein(a) assay and apolipoprotein(a)-based assay