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Tag: Chemotherapy

The 21-gene recurrence score (Oncotype DX) seems to accurately identify women with early-stage breast cancer who don't need chemotherapy

Gene Test IDs Breast CA Patients Who May Not Need Chemo

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Analysis can help women who won't benefit from additional treatment to avoid side effects
For patients with sinonasal squamous cell carcinoma

Neoadjuvant Chemo Response Predicts Sinonasal SCC Outcomes

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Better overall survival, disease-free survival, locoregional control, freedom from metastases
Dose-dense weekly paclitaxel does not improve progression-free survival in ovarian cancer

Weekly Paclitaxel Doesn’t Up Survival in Ovarian Cancer

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Among patients not receiving bevacizumab, weekly paclitaxel tied to improved progression-free survival
Vitamin E supplementation can reduce cisplatin-induced ototoxicity

Vitamin E Neuroprotective Against Cisplatin Ototoxicity

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Placebo group had significant hearing loss at one month at both 2,000 HZ and 8,000 HZ
Cola intake leads to a clinically relevant and statistically significant increase in the bioavailability of erlotinib during esomeprazole treatment

Cola Intake Increases Exposure of Erlotinib

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Findings in patients treated with esomeprazole; likely due to pH-dependent solubility
For patients with early-stage small-cell lung cancer undergoing resection

Adjuvant Therapy Ups Survival in Small-Cell Lung Cancer

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Improved survival for chemotherapy with or without cranial irradiation versus surgery alone
For patients with locally advanced bladder cancer

Cystectomy Plus Chemo Ups Survival in Bladder Cancer

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Improved survival with adjuvant chemotherapy in patients with locally advanced disease
For patients with rectal cancer

ASCO: New Regimen Effective for Locally Advanced Rectal Cancer

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Similar effectiveness but less toxicity for short-course radiation followed by chemotherapy
For patients with stage III colon cancer treated with leucovorin

KRAS, BRAF V600E Mutations Impact Survival in Colon Cancer

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Mutations linked to shorter survival in patients with microsatellite-stable tumors
For women with breast cancer treated with primary systemic chemotherapy

Axillary pCR Linked to Improved Breast Cancer Survival

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Very high survival for axillary pathologic complete response for women with HER2-positive disease