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Tag: Chemotherapy

For myeloma patients with progressive disease (PD) after induction therapy

Salvage Therapy Does Not Up Survival for Progressive Myeloma

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Deepening of response through salvage therapy not linked to improved progression-free, overall survival
Survivors of childhood cancer have an increased risk for all subtypes of cardiovascular disease

Risk for Cardiovascular Disease Greater for Childhood Cancer Survivors

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Exposure to ≥250 mg/m² doxorubicin-equivalent anthracycline chemo tied to risk for CVD, heart failure
Delay in initiation of chemotherapy is associated with poorer overall survival for breast cancer

Delay in Time to Chemo Impacts Survival in Breast Cancer

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Time interval from diagnosis to surgery has largest impact on time from diagnosis to chemo initiation
Photobiomodulation

Light Therapy May Prevent Oral Mucositis for Some in Cancer Tx

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Laser, other light tx recommended for patients treated with HSCT; head and neck RT with, without chemo
A substantial proportion of older patients with high-risk acute myeloid leukemia treated with chemotherapy are long-term survivors

High Response Seen for Chemo in Seniors With High-Risk AML

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Complete response rate for patients treated with chemo was 69 percent; three-year OS was 21 percent
For patients with stage III or IVA endometrial cancer

Chemoradiation Does Not Up Survival in Endometrial Cancer

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Distant recurrence more common with chemoradiation versus chemotherapy in stage III, IVA disease
Polivy (polatuzumab vedotin-piiq)

Chemoimmunotherapy Regimen Approved to Treat DLBCL

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Polivy approved in combination with bendamustine, rituximab for diffuse large B-cell lymphoma
For frail and elderly patients with advanced gastroesophageal cancer

ASCO: Low-Dose Chemo Benefits Advanced Gastroesophageal Cancer

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Elderly, frail receiving 60 percent of oxaliplatin/capecitabine dose have noninferior PFS, less toxicity
Pembrolizumab is noninferior to chemotherapy for overall survival among patients with programmed death ligand 1

ASCO: Pembrolizumab Noninferior to Chemo in Advanced Gastric Cancer

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For patients with PD-L1 combined positive score of ≥10, pembrolizumab prolongs overall survival
Octogenarians with acute myeloid leukemia have a one-month mortality rate of 41 percent and overall survival of 1.5 months

Octogenarians With Acute Myeloid Leukemia Have Poor Survival

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Overall survival 1.5 months; survival improved for those receiving chemotherapy