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Tag: Cancer: Skin

From 2000 to 2012 there was an increase in the incidence of sebaceous carcinoma

Incidence of Sebaceous Carcinoma Up From 2000 to 2012

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Higher all-cause mortality among males, blacks, and for extraocular anatomic locations
Certain patients at high risk of melanoma may benefit from more tailored skin exams

Clinical Features Can Be Used to Tailor Melanoma Screening

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A tailored surveillance program could lead to greater precision in melanoma prevention
Patients with melanoma treated with a combination of ipilimumab and nivolumab may be at risk for a potentially fatal T-cell-driven drug reaction

Myocarditis ID’d With Ipilimumab + Nivolumab in Melanoma

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Case report describes two patients who developed fatal T-cell-driven drug reaction
In an non-integrated dermatopathology practice

Use of Term ‘Rule Out’ May Delay Dermatopathology Diagnosis

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Use on requisition form linked to longer time to diagnosis, increased use of pathology stains, sections
For patients with cutaneous melanoma

Whites Have Longest Survival in Cutaneous Melanoma

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For stages I and III, black patients have significantly lower survival, increased hazard ratios
Mohs micrographic surgery is efficacious for melanoma in situ (MIS) on the trunk and proximal extremities

Mohs Effective for Melanoma in Situ of Trunk, Extremities

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Surgical margin of 9 mm needed to excise 97 percent of melanoma in situ
More than half of melanomas are self-detected

More Than Half of Melanomas Are Self-Detected

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Self-detection by women ups prognosis; men have more melanomas in non-easily visible locations
For patients with lentigo maligna in-situ melanoma

pCR of 37 Percent for Topical Imiquimod in Lentigo Maligna

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With imiquimod cure rate of 80 percent, half of surveyed patients preferred imiquimod over surgery
A psychoeducational intervention is effective for reducing fear of cancer recurrence among patients with ongoing melanoma care

Psychoeducational Intervention Reduces Fear of CA Recurrence

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Newly developed intervention effective for reducing FCR, stress, and increasing melanoma knowledge
Radiotherapy is effective in regional control of node-positive malignant melanoma

Radiotherapy Aids Regional Control of Node+ Melanoma

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However, risk of early distant relapse is close to 50 percent