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Tag: Cancer: Skin

About 30 percent of indoor tanners have been screened for skin cancer

Few Indoor Tanners Have Been Screened for Skin Cancer

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Correlates of screening include older age, family history of melanoma or skin cancer, high SPF sunscreen use
Use of the diuretic hydrochlorothiazide is associated with a substantially increased risk of non-melanoma skin cancer

Hydrochlorothiazide Tied to Non-Melanoma Skin Cancer Risk

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Dose-response association seen for basal cell and especially squamous cell carcinoma
Strains of Staphylococcus epidermidis producing 6-N-hydroxyaminopurine may provide protection against skin neoplasia

S. epidermidis Producing 6-HAP May Protect From Skin Neoplasia

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6-HAP selectively inhibited proliferation of tumor lines in culture; cut incidence of UV-induced tumors in mice
The most frequent dermoscopic criteria for melanoma in situ are regression

Dermoscopic Criteria Identified for Diagnosing Melanoma in Situ

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Most frequent dermoscopic criteria for MIS are regression, atypical network, irregular dots/globules
For men with metastatic melanoma treated with targeted or immune therapy

Obesity Linked to Improved Survival in Metastatic Melanoma

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Survival benefit limited to male patients receiving targeted therapy, immunotherapy
In recent years there has been an increase in melanoma incidence

2005 to 2014 Saw Increase in Melanoma Incidence

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For males and females combined, incidence fell for those aged 15 to 44, increased for those ≥55
The incidence of squamous cell carcinoma affecting the eyelids is rising in England

Eyelid Squamous Cell Carcinoma Rate Increasing in England

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Older age and male sex, but not social deprivation, are associated with higher eyelid SCC risk
Guidelines of care have been developed for the management of basal cell carcinoma and cutaneous squamous cell carcinoma

Guidelines of Care Developed for Skin Cancer Management

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Recommendations for basal cell carcinoma, cutaneous squamous cell carcinoma released
Patients with desmoplastic melanoma have a high level of objective tumor response to treatment with antibodies to block programmed cell death 1 (PD-1) or PD-1 ligand

High Response of Desmoplastic Melanomas to PD-1 Blockade

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Higher percentage of PD-L1-positive cells in the tumor parenchyma of desmoplastic melanomas
Fluorouracil application can reduce the risk of surgery for squamous cell carcinoma for one year among patients with a history of keratinocyte carcinomas

Fluorouracil Tied to Reduced Surgery for Squamous Cell CA

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Reduced risk of squamous cell carcinoma, but not basal cell carcinoma, for one year in at-risk veterans