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Tag: Cancer: Prostate

The rate of germline BRCA1/2 and ATM mutations is significantly higher among patients with lethal prostate cancer and is an independent predictor of lethal prostate cancer

BRCA1/2, ATM Mutations ID Risk for Lethal Prostate Cancer

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After adjustment for covariates, mutation carrier remained independent predictor of lethal PCa
Magnetic resonance imaging (MRI) and MRI-targeted biopsies have a role in the diagnosis and treatment of patients with a prior negative prostate biopsy

MRI Has a Role to Play After Negative Prostate Biopsy

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Magnetic resonance imaging, MRI-targeted biopsy facilitate detection of clinically significant disease
For patients with prostate cancer

Methylation of PITX2 DNA Feasible in Prostate Biopsies

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Can add prognostic information for risk assessment in presurgical diagnostic setting
For men with advanced prostate cancer

Mindfulness-Based Tx Doesn’t Cut Distress in Prostate Cancer

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No significant changes in intervention outcomes for mindfulness-based cognitive therapy in advanced PC
For men with prostate cancer

ADT Use Not Linked to Dementia in Prostate Cancer

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No increased risk of dementia for androgen deprivation therapy use versus nonuse
In a consensus statement from the American Urological Association and Society of Abdominal Radiology

Guidelines Developed for Prostate MRI After Negative Biopsy

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Prostate MRI, MRI-targeted cores can facilitate detection of significant disease over repeat biopsy
Exercising during and after cancer treatment is safe and improves quality of life

Cancer Patients Benefit From Exercise During, After Treatment

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Studies show better physical function, quality of life for those who did strength training, aerobic activity
Second opinions have little impact on prostate cancer patients' treatment decisions

Second Opinions Seldom Change Prostate Cancer Decisions

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Most patients choose treatment they originally planned to follow
For screened men enrolled in prostate cancer prevention trials

Differences in Risk Factor Estimates for Prostate Cancer

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Across cohorts of men undergoing screening, considerable variation in risk factor estimates
For men with low-risk prostate cancer

Higher Grade Disease at Prostatectomy With Surveillance

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No difference in other adverse pathological outcomes versus men undergoing immediate surgery