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Tag: Cancer: Prostate

Germline Genetic Testing Feasible for Advanced Prostate Cancer

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High satisfaction reported for genetic testing model including education, follow-up with genetic counselor

Guideline Updated for Initial Management of Advanced Prostate Cancer

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Triplet therapy should be offered to patients with de novo metastatic noncastrate prostate cancer with high-volume disease

Active Surveillance for Low-, Intermediate-Risk Prostate Cancer on the Rise

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However, significant differences in use seen by race/ethnicity, education, and geography

Initiating Salvage RT When PSA >0.25 ng/mL Linked to All-Cause Mortality

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Risk for all-cause mortality up for men receiving post-radical prostatectomy salvage radiation therapy at PSA level >0.25 ng/mL

Long-Term Waterborne-Ingested Nitrate Linked to Prostate Cancer Risk

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Higher associations seen for those with lower intakes of fiber, fruit/vegetables, and vitamin C

Clinical Utility Poor for Prostate Cancer Germline Panels in African Men

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Seventeen variants identified as potentially oncogenic in 17.7 percent of South African male patients

Digital Rectal Exam Does Not Detect Early-Stage Prostate Cancer

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Among men analyzed with DRE as solitary screening test for prostate cancer, suspicious findings did not increase prostate cancer detection

2014 to 2021 Saw Increase in Use of Active Surveillance for Low-Risk Prostate Cancer

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Considerable variation observed in active surveillance use, from 4.0 to 78.0 percent at practice level and from 0 to 100 percent at practitioner level

Nine Novel Prostate Cancer Variants Identified in Men With African Ancestry

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Multiancestry polygenic risk score can stratify prostate cancer risk and differentiate risk for aggressive disease

Magnitude of Reduction in PSA Level May Indicate Outcomes in Prostate Cancer

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Findings seen for men treated with enzalutamide for nonmetastatic castration-resistant prostate cancer