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Home Tags Cancer: Ovarian

Tag: Cancer: Ovarian

For women with epithelial ovarian cancer

Adjuvant Hormone Tx Ups Survival in Epithelial Ovarian CA

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Significant improvement in overall, relapse-free survival for women receiving five-years of AHT
Eudaimonic well-being is associated with lower tumor norepinephrine in women with epithelial ovarian cancer

Eudaimonic Well-Being Tied to Ovarian Tumor Neuroeffector

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Positive affect, psychological distress not associated with tumor norepinephrine
Nonselective beta-blocker use is associated with improved overall survival among patients with epithelial ovarian

Nonselective Beta-Blocker Use Ups Survival in Ovarian Cancers

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Longer median overall survival for patients receiving any beta-blocker versus nonusers
Deleterious mutations in RAD51C and RAD51D genes are associated with increased risk of epithelial ovarian cancer

RAD51 Mutations Confer Moderate Risk of Ovarian Cancer

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RAD51C and RAD51D deleterious mutations linked to increased risk of epithelial ovarian cancer
Multigene testing for hereditary breast and/or ovarian cancer identifies more mutations that are likely to change clinical management

Multigene Test IDs More at Risk for Hereditary Breast/Ovarian CA

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Testing for mutations other than BRCA1/2 in HBOC may change clinical management for women, families
About thirty percent of women with epithelial ovarian cancer survive for more than 10 years

~30 Percent With Epithelial Ovarian CA Survive Long Term

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Predictors for long-term survival include younger age, early stage, low grade, non-serous histology
Intraperitoneal chemotherapy significantly improves survival among women with advanced ovarian cancer; however

Intraperitoneal Chemotherapy Ups Ovarian Cancer Outcomes

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However, only 41 percent of suitable candidates actually receive the therapy
The R-enantiomer of ketorolac is enriched in peritoneal fluids and inhibits peritoneal cell GTPase activity with administration after ovarian cancer surgery

Novel Pharmacological Activity for R-Ketorolac in Ovarian Cancer

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R-enantiomer enriched in peritoneal fluids, inhibits peritoneal cell GTPase activity
Chemotherapy dose reduction is associated with worse survival in ovarian cancer

Worse Survival With Chemo Dose Reduction in Ovarian Cancer

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Lower average relative dose intensity linked to worse overall and ovarian cancer-specific survival
Undergoing chemotherapy before surgery may help women battling advanced ovarian cancer

Benefits for Surgery Before Chemo in Advanced Ovarian CA

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Appears to raise quality of life without shortening survival