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Tag: Cancer: Esophageal

Oral microbiome composition is associated with the risk of esophageal adenocarcinoma and esophageal squamous cell carcinoma

Oral Microbiome Composition Linked to Esophageal Cancer Risk

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Periodontal pathogen Tannerella forsythia linked to increased risk of esophageal adenocarcinoma
Ramucirumab appears to be safe and effective for the treatment of advanced gastric cancer

Ramucirumab Shows Promise in Care of Advanced Gastric Cancer

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In two separate trials, hazard ratios for overall survival favor treatment with ramucirumab
Rates of major upper abdominal cancer resections in octogenarians are increasing

Upper Abdominal Cancer Resections Up in Octogenarians

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Increase in resection rates driven by trends in hepatic and pancreatic resections
Adjuvant chemotherapy is associated with improved survival for patients with locally-advanced gastroesophageal adenocarcinoma treated with preoperative chemoradiotherapy and resection

Adjuvant Chemo Beneficial in Advanced Gastroesophageal CA

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Improved overall survival for patients with locally-advanced gastroesophageal adenocarcinoma
For patients with locally advanced esophageal carcinoma who received neoadjuvant chemoradiotherapy

Females Show Better Response to CRT in Esophageal Cancer

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Females more often had complete, nearly complete pathologic response to induction tx; less recurrence
There is a low risk of development of high-grade dysplasia or esophageal adenocarcinoma among patients with Barrett's esophagus of <1 cm (irregular Z line) within five years of index endoscopy

Barrett’s With Irregular Z Line Unlikely to Progress Quickly

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Within five years, incident cancer cases observed only in patients with Barrett's esophagus ≥1 cm
Overweight young adults may have a significantly increased risk of esophageal adenocarcinoma and gastric cardia adenocarcinoma if they become obese later in life

Esophageal Cancer Risk Rises Alongside Weight

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Research also shows association with increased odds for gastric cardia adenocarcinoma
For patients with Barrett's esophagus

No Chemopreventive Effect Seen for H2RAs in Barrett’s Esophagus

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PPI use, but not H2 receptor antagonists, linked to reduced risk of progression in Barrett's esophagus
A breath test to detect esophageal and gastric cancers shows promise

Breath Test to Detect Esophageal, Gastric Cancers May Be Feasible

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Test could reduce the number of unnecessary endoscopies, researcher says

ASCO Gastrointestinal Cancers Symposium, Jan. 19-21

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The 2017 Gastrointestinal Cancers Symposium The American Society of Clinical Oncology's 13th annual Gastrointestinal Cancers Symposium was held from Jan. 19 to 21...