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Tag: Cancer: Breast

Hypofractionated radiation therapy with incorporated boost over a shorter period of time treats early-stage breast cancer as well as longer

ASTRO: Shorter Radiation OK for Early Breast Cancers

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High-dose therapy shows same survival rates as longer course of standard radiation
Girls from families with a history of breast cancer experience greater breast cancer-specific distress

Greater Breast CA-Specific Distress for Girls With Family Hx

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No difference in psychosocial adjustment for girls with versus without family history of breast cancer
A combination of breast conservation surgery and radiation is as effective as breast removal for some women with large

Not All Large Breast Tumors Warrant Mastectomy

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Findings suggest doctors shouldn't automatically rule out less invasive surgery plus radiation
There were substantial shifts in treatment patterns for ductal carcinoma in situ from 1991 to 2010

Treatment Patterns for DCIS Shift From 1991 to 2010

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Highest proportion of patients opts for lumpectomy and radiation therapy
Women in certain racial/ethnic groups are more likely to be diagnosed with more advanced breast cancer

Advanced-Stage Breast CA More Likely in Certain Racial Groups

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African-American, white Hispanic women more likely to receive non-guideline-concordant treatment
Even with recent strides in breast cancer treatment

Early Detection Still Key to Breast Cancer Survival

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Despite advances in treatment, finding smaller tumors linked to better results
Only about one-third of women receive genetic counseling before they undergo testing for BRCA mutations

Too Few Women Getting Counseling Before BRCA Test

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But outside expert questions whether counseling may be more important after a positive test result
A 21-gene risk of recurrence score can identify patients with breast cancer who may be spared chemotherapy

Prospective Validation of 21-Gene Risk of Recurrence Score

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Score identifies breast cancer patients with low risk of recurrence who may be spared adjuvant chemo
Greater numbers of high-risk women eligible for primary prevention of breast cancer are identified by incorporating benign breast disease diagnoses into the Breast Cancer Surveillance Consortium risk model

Adding Benign Breast Dz to Risk Model May Boost Preventive Care

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Found to increase the number of high-risk women deemed eligible for primary prevention
From 2003 to 2102 there was a significant increase in preoperative breast magnetic resonance imaging use in women with breast cancer

Preoperative Breast MRI Use Increased From 2003 to 2012

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Eight-fold increase during 10-year period; MRI use linked to more ancillary investigations