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Tag: Cancer: Breast

African-American women with type 2 diabetes appear to be at increased risk of developing estrogen receptor-negative (ER-) breast cancer

ER- Breast CA Risk Up for African-Americans With T2DM

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ER- type accounts for increased breast cancer risk in African-American women; highest risk in nonobese
When adjuvant endocrine therapy for estrogen receptor-positive breast cancer is stopped after five years

Breast Cancer Recurrences Steady After Therapy Cessation

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Women with ER-positive BC who stop therapy after 5 years have steady recurrence rate up to 20 years
After adoption of the Affordable Care Act

Incidence of Early-Stage Breast CA, CRC Up With ACA Adoption

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No change in incidence of locally advanced or metastatic-stage cancer after ACA adoption
PARP inhibitors demonstrate activity in triple-negative breast cancer tumors without BRCA1/2 mutations

PARP Inhibitors Promising Beyond BRCA1/2 Altered Tumors

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Talazoparib caused regression in 5 patient-derived xenografts, 4 without germline BRCA1/2 mutations
The combination of elastography and color Doppler ultrasonography with B-mode US in women with dense breasts can increase the positive predictive value of screening and reduce the number of false-positives

Elastography and Color Doppler Improve Breast Ultrasound

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Together, the technologies increase predictive value of screening while decreasing unnecessary biopsies
Automated breast ultrasonography may not be of added value to yearly full-field digital mammography and dynamic contrast agent-enhanced magnetic resonance imaging surveillance of carriers of the BRCA mutation

Multimodal Surveillance Regimen May Not Benefit BRCA Carriers

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Biannual automated breast ultrasound may not add value to annual mammography, MR imaging
The 70-gene signature assay affects treatment decisions among physicians treating patients identified as being at intermediate risk with the 21-gene assay

70-Gene Signature Impacts Treatment Decisions in Breast CA

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70-GS linked to change in treatment decisions for intermediate-risk patients based on 21-gene assay
Swedish massage therapy is associated with clinically significant relief from cancer-related fatigue in breast cancer survivors

Swedish Massage May Reduce Cancer-Related Fatigue

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For breast cancer survivors, larger drop in fatigue scores with Swedish massage than light touch
Cryotherapy may be useful for preventing symptoms of chemotherapy-induced peripheral neuropathy

Cryotherapy May Prevent Chemo-Induced Neuropathy

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Breast cancer patients on paclitaxel had lower incidence of peripheral neuropathy with cryotherapy
A machine learning model can predict the risk of upgrade of high-risk breast lesions to cancer

Machine Learning Model Predicts Risk of Upgrade to Breast CA

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Model can predict risk of upgrade of high-risk breast lesions to cancer using traditional, text features