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Tag: Cancer: Brain

There are noticeable differences in hospice utilization among patients with malignant glioma

Variation Seen in Hospice Use for Malignant Glioma

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Differences by race, sex, age, level of education, urban versus rural residence identified
In patients with progressive glioblastoma

Drug Combo Doesn’t Lengthen Glioblastoma Survival

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Lomustine+bevacizumab may increase progression-free, but not overall, survival versus lomustine alone
Overall survival for patients with melanoma brain metastases has improved significantly since 2000

Overall Survival Up for Melanoma Brain Metastases

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Median overall survival from time of diagnosis has increased from 7.5 to 22.7 months
An experimental vaccine therapy shows promise in treating glioblastoma

Vaccine-Chemotherapy Combo Promising in Glioblastoma

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Four of the 11 patients in study survived for more than five years after vaccine/chemo treatment
Adding tumor-treating fields to temozolomide is associated with improved progression-free and overall survival in glioblastoma

AACR: TTFields + Temozolomide Ups Survival in Glioblastoma

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Compliance with TTFields treatment predicts outcome, with better outcome for >18 hour/day
There's no link between cytomegalovirus and glioblastoma or other high-grade gliomas

Study Finds No Link Between Cytomegalovirus, Glioblastoma

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Researchers find no evidence of cytomegalovirus in tumor tissue
Treatment with autologous chimeric antigen receptor-engineered T cells targeting the tumor-associated antigen interleukin-13 receptor alpha 2 is associated with tumor regression in recurrent multifocal glioblastoma

Case Report: Adoptive T-Cell Tx Shows Promise in Glioblastoma

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Tumors regressed after intracranial infusions of T cells engineered to target tumor-associated antigen
A radiomic-based approach can be used to generate a prediction model for stratifying treatment outcome among patients with recurrent glioblastoma prior to bevacizumab treatment

Radiomic-Based Method Predicts Recurrent Glioblastoma Outcome

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Radiomic-based superpc signature stratifies patients into low- or high-risk groups for PFS, OS
For some metastatic brain cancer patients

Less Cognitive Deterioration With Stereotactic Radiosurgery Alone

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Results seen in patients with one to three brain metastases
More extensive surgeries may best optimize patient survival in glioblastoma multiforme

Gross Total Resection for the Best Results in Glioblastoma

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Although larger procedure carries more risk, odds of longer survival are higher