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Tag: Cancer: Bladder

Loss of argininosuccinate synthetase 1

ASS1 Loss Identified in Invasive Bladder Cancer

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ASS1-deficient cells were preferentially sensitive to ADI-PEG 20, as shown by reduced cell viability
Patients with muscle invasive bladder cancer who undergo neoadjuvant chemotherapy before and after radical cystectomy frequently experience thromboembolic events

Thromboembolic Events Common With Chemo for Bladder Cancer

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Findings in patients with muscle invasive bladder cancer who undergo neoadjuvant chemotherapy
Low vitamin D levels may increase the risk of bladder cancer

Bladder Cancer Risk Correlates With Low Serum Vitamin D

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Researchers find that bladder epithelial cells activate and respond to vitamin D
For patients undergoing robot-assisted radical cystectomy

Factors ID’d for Recurrence After Radical Cystectomy

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Pathological tumor characteristics mainly predict recurrence after robot-assisted radical cystectomy
Early unexpected recurrences after laparoscopic radical cystectomy occur in 8.7 percent of patients with favorable pathological characteristics

Study Looks at Recurrence After Laparoscopic Radical Cystectomy

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During first 24 months, 8.7 percent of patients with favorable pathological characteristics had progressed
Among patients with stage IV bladder cancer

Sex Disparities in Chemo Use for Advanced Bladder Cancer

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Women have lower median overall survival, even after adjustment for administration of chemo
Patient experience is associated with urologic cancer surgical outcomes

Patient Experience Linked to Urologic CA Surgical Outcomes

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Less prolonged hospitalization, fewer nursing-sensitive complications in high-performing hospitals
Patients with advanced bladder cancer may benefit from the anti-PD-L1 immunotherapy atezolizumab (Tecentriq)

ASCO: Immunotherapy Beneficial in Advanced Bladder Cancer

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About a quarter of older patients deemed too frail for chemo responded to atezolizumab
The U.S. Food and Drug Administration has approved atezolizumab (Tecentriq)

FDA Approves Tecentriq to Treat Urothelial Carcinoma

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FDA also approves a companion test to detect PD-L1 protein expression levels in patients
Arsenic in drinking water from private wells may explain the elevated bladder cancer risk among people in three New England states

Well Water a Suspected Cause of Bladder Cancer in New England

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Researchers believe arsenic exposure might contribute to higher-than-normal rates