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April 2016 Briefing – Neurology

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Here are what the editors at HealthDay consider to be the most important developments in Neurology for April 2016. This roundup includes the latest...
Plasma homocysteine and its metabolite homocysteine thiolactone contribute to Alzheimer's disease pathology via the amyloid-β-fibrinogen interaction

Homocysteine Tied to Alzheimer’s Via Aβ-Fibrinogen Interaction

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Elevated levels of plasma HC/HCTL contribute to Alzheimer's pathology via Aβ-fibrinogen interaction
Children with congenital infection

Severe Cerebral Damage ID’d on Imaging in Children With Zika

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Findings seen in 23 children with congenital infection, presumably associated with Zika virus
Growth charting methods identify a correlation between intrinsic connectivity networks and attention performance

Brain Network Charts Could Help Predict Attention Impairment

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Correlation between intrinsic connectivity networks, attention performance in youths
The Zika virus may be linked to acute disseminated encephalomyelitis

AAN: Zika May Be Linked to Acute Disseminated Encephalomyelitis

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Researchers in Brazil detect symptoms similar to multiple sclerosis
Autosomal dominant Alzheimer's disease is associated with increased white matter hyperintensities on magnetic resonance imaging well before expected symptom onset

White Matter Hyperintensities Predate Alzheimer’s Onset

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White matter hyperintensity volume differences seen six years before symptoms
For combat veterans with posttraumatic stress disorder

Novel Mindfulness-Based Group Therapy Beneficial in PTSD

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For combat veterans, increased connectivity with DLPFC and dorsal ACC following therapy
Adding chemotherapy to radiation treatment may add years to the lives of patients with grade 2 gliomas

Adding Chemo May Prolong Lives of Some Grade 2 Glioma Patients

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Those with slow-growing gliomas lived five years longer, on average, than those who got only radiation
For patients with primary insomnia

White Matter Tract Changes in Right Brain in Insomnia

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Primary insomnia patients have lower FA values in seven regions in the right brain
A long-term weight loss intervention may reduce the impact of diabetes on brain structure

Long-Term Weight Loss Cuts Diabetes-Related Brain Changes

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10-year weight loss intervention tied to lower white matter hyperintensity volume