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HIV-positive individuals treated with combination antiretroviral therapy have poorer neuropsychological test scores than controls but no significant neuropsychological decline over time

Poorer Neuropsychological Test Scores for HIV-Positive

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No significant neuropsychological decline during two-year period with combination antiretroviral therapy
Among older adults

Cardiac Index Linked to Cerebral Blood Flow Regardless of CVD

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No link for cardiac index with CBF in regions other than temporal lobes, cerebrovascular reactivity
Concentrations of cerebrospinal fluid β42-amyloid 42 derived from new immunoassays may show improved agreement with visual flutemetamol F18-labeled positron emission tomography assessment

Benefits for New Immunoassays for Measuring Aβ42 in CSF

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May show improved correlation with mass spectrometry reference measurement procedure
For patients with chronic valvular heart disease

Brain Measures Tied to Atrial Pressure in Valvular Heart Dz

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Linear link between white matter hyperintensity volume, RA pressure in chronic valvular heart disease
Systemic inflammation in midlife is associated with future neurodegeneration and cognitive aging

Midlife Systemic Inflammation Tied to Late-Life Brain Volume

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Smaller hippocampal, Alzheimer's signature region volumes seen 24 years after inflammation noted
Black men have increased prevalence and frequency of multiple intracranial atherosclerotic plaques

Race a Factor in Intracranial Atherosclerotic Disease

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Prevalence and frequency of multiple plaques were higher for black men
Hypothermia treatment initiated at six to 24 hours after birth for newborns with hypoxic-ischemic encephalopathy may reduce death or disability

Hypothermia May Help Newborns With Encephalopathy

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Appears to reduce death, disability in infants with encephalopathy, but effectiveness uncertain

September 2017 Briefing – Neurology

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Here are what the editors at HealthDay consider to be the most important developments in Neurology for September 2017. This roundup includes the latest...
For patients with progressive multifocal leukoencephalopathy

Caution for PLEX in Progressive Multifocal Leukoencephalopathy

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Plasma exchange not linked to PML immune reconstitution inflammatory syndrome latency
Patients with severe neurotoxicity after infusion of CD19-targeted chimeric antigen receptor-modified T cells have evidence of endothelial activation

Neurotoxicity Characterized After Infusion of CD19 CAR-T Cells

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Patients with severe neurotoxicity have endothelial activation, increased BBB permeability