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Negative fateful life events in midlife are associated with advanced predicted brain aging

Negative Fateful Life Events Linked to Advanced Brain Aging

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More midlife FLEs, especially relating to interpersonal relationships, tied to advanced predicted brain aging
One night of sleep deprivation is associated with amyloid-β burden in healthy controls

One Night of Sleep Deprivation Linked to Amyloid-β Burden

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Increase in Aβ burden in right hippocampus and thalamus after one night of sleep deprivation
There are significant differences in the development of 12 fiber tracts between infants with fragile X syndrome and controls

White Matter Tracts Differ for Infants With Fragile X Syndrome

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Significant differences identified in the development of 12 fiber tracts between FXS, controls
Type 1 diabetes is associated with cognitive dysfunction in children

Glycemic Extremes in T1DM Impact Cognitive Skills in Kids

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Meta-analysis shows lower intelligence, diminished attention, slower psychomotor speed with T1DM
Healthy older subjects display preserved neurogenesis in the Hippocampus

Preserved Neurogenesis in Hippocampus of Healthy Seniors

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Older adults have less angiogenesis, neuroplasticity; smaller quiescent progenitor pool in anterior-mid DG
Anomalous brain development is evident among medication-naive preschoolers with attention-deficit/hyperactivity disorder

Anomalous Brain Structure ID’d in Preschoolers With ADHD

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Reductions in bilateral frontal, parietal, and temporal lobe gray matter volumes in ADHD
For patients with major depressive disorder

Relapse in Major Depression Linked to Brain Cortical Changes

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Significant decline of insular volume and dorsolateral prefrontal from baseline to follow-up
In neurotypical development

Amygdala Neurons Reduced in Adulthood With Autism

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This is in contrary to normal neurologic development where mature neurons increase into adulthood
Taking menopausal hormone therapy may have long-term effects on the brain

Hormone Therapy May Impact Brain Structure, Cognition

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But 3 years after menopausal HT, change in brain volumes not significantly different from placebo
Young adults with type 1 diabetes have altered neural responses during working memory processing

Altered Neural Responses in Memory Processing in T1DM

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Significantly stronger neural responses in superior parietal cortices during memory encoding in T1DM