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Greater genetic predisposition for multiple sclerosis is associated with altered brain white matter development at an early age

Brain Changes From Multiple Sclerosis May Occur in Preteens

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Greater genetic predisposition for MS tied to imaging-observable changes in white matter in preteens
Sleep-disordered breathing is associated with changes in the brain

Sleep-Disordered Breathing Tied to Brain Changes

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Greater amyloid burden seen in regions of the brain tied to Alzheimer disease
Bumetanide seems effective for improving symptoms of autism spectrum disorder in young children

Bumetanide Promising for Reducing Autism Symptoms

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Decrease in GABA/glutamate ratio in insular cortex tied to symptom improvement in bumetanide group
For young adults with supratentorial intracerebral hemorrhage

Supratentorial ICH Outcomes Better in Young Blacks, Hispanics

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Outcomes better compared with whites among young adults with supratentorial intracerebral hemorrhage
Most external ventricular drain closures performed in patients with subarachnoid hemorrhage last less than one minute

Longer External Ventricular Drain Closures Needed to Read ICP

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Intracranial pressure equilibrium reached in only 22.9 percent of external ventricular drain closures
From 2001 to 2016

2001 to 2016 Saw Drop, Stall in IQ Losses From Chemicals

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IQ losses due to in utero PBDE, methylmercury exposure, early life lead exposure decreased or stalled
Cardiorespiratory fitness is positively associated with gray matter volume and total brain volume and with gray matter volume in specific brain areas

Cardiorespiratory Fitness Linked to Gray Matter Volume

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Strong association found for VO2peak with GM volume of left middle temporal gyrus, right hippocampal gyrus
The global intensity of the tau-positron emission tomography signal predicts the rate of subsequent atrophy in patients at early symptomatic Alzheimer disease stages

Tau-PET Signal Predicts Atrophy in Early Alzheimer Disease

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Association between baseline tau-PET and subsequent atrophy particularly strong in younger patients
Resting-state functional magnetic resonance imaging measures may be able to predict symptoms of attention-deficit/hyperactivity disorder or major depressive disorder in children

fMRI Measures May Predict Psychiatric Symptoms in Children

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Less positive coupling between sgACC, DLPFC at age 7 linked to increase in internalizing behaviors at 11
Individuals with objectively-defined subtle cognitive difficulties have faster amyloid accumulation and faster entorhinal cortical thinning compared with cognitively normal individuals

Subtle Cognitive Difficulties May Predict Amyloidosis

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Individuals with objectively-defined SCD have faster amyloid accumulation, entorhinal cortical thinning