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Brain scans may predict which type of therapy will be most effective for obsessive-compulsive disorder in teens and adults

Brain Scan May Guide Therapy for Obsessive-Compulsive Disorder

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Better response to cognitive behavioral therapy linked to greater activation in certain areas of brain
Black Americans have a higher incidence of cerebral venous thrombosis compared with other races

Blacks Have Higher Incidence of Cerebral Venous Thrombosis

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Increases in the incidence of CVT from 2006 to 2016 driven mainly by increases among men, older women
There are longitudinal changes in the microstructure and function of the brain in otherwise healthy

Brain Changes Identified in Nonconcussed Contact Athletes

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Changes in brain microstructure, function seen in asymptomatic contact versus noncontact athletes
Mental stress-induced inferior frontal lobe activation is associated with angina among patients with coronary artery disease

Mental Stress-Induced Brain Activation Linked to Angina

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Mental stress-induced inferior frontal lobe activation linked to angina in stable coronary artery disease
Years of education and the ε4 risk allele at APOE influence β-amyloid pathology in asymptomatic individuals with a parental history of sporadic Alzheimer disease (AD)

Education May Affect β-Amyloid Burden in Alzheimer Disease

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Findings seen in two cohorts with parental history of sporadic AD, autosomal dominant AD
World Trade Center (WTC) responders with cognitive impairment have reductions in cortical thickness

WTC Responders With Impaired Cognition Have Brain Changes

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Another study IDs plasma proteins associated with PTSD, MCI, both in World Trade Center responders
Early-life adversity is associated with accelerated biological aging

Early-Life Adversity Associated With Accelerated Biological Aging

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Links vary by adversity type; threat-related early-life adversity tied to accelerated pubertal development
Among patients with unruptured brain arteriovenous malformation

Medical Management Alone Better for Brain AV Malformations

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Risk of stroke or death up with medical management plus interventional therapy for unruptured AVM
Patients with Alzheimer disease have increased iron concentration in the deep gray matter and neocortical regions compared with healthy controls

Brain Iron Concentrations Increased in Alzheimer Disease

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Increased iron concentration seen in deep gray matter, neocortical regions versus healthy controls
Cognitively normal women have increased Alzheimer disease endophenotype

Women Have More Brain Changes Related to Alzheimer Disease

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Menopausal status the predictor most consistently and strongly linked to brain differences, after sex