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Home Tags Birth Defects: Misc.

Tag: Birth Defects: Misc.

In 2020 European Society of Cardiology guidelines

ESC Updates Guidelines for Adult Congenital Heart Disease

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Patients with congenital heart disease increasingly present as older adults, including the elderly
Changes have been suggested for the newborn critical congenital heart disease screening algorithm

Changes Proposed for Newborn Congenital Heart Disease Screen

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Oxygen saturation of at least 95 percent in both upper, lower extremities required to pass
For eight cancer types

Tumors of Embryonic Origin More Common in Children With Birth Defects

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Most common childhood cancer, acute lymphoblastic leukemia, seen at lower frequency in children with birth defects
Use of oral fluconazole for treatment of vulvovaginal candidiasis in the first trimester of pregnancy is associated with musculoskeletal malformations

Musculoskeletal Malformations Up With Fluconazole in Pregnancy

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But no increase seen in conotruncal malformations, oral clefts with use of oral fluconazole in first trimester
From 2003 to 2017

2003 to 2017 Saw Drop in Infant Mortality Due to Birth Defects

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Considerable variation found in the decrease, with smallest decline for infants born to black mothers
Psychological distress

Maternal Distress May Affect Brain Development in Fetuses With CHD

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Stress, anxiety, depression more prevalent among women carrying fetuses with congenital heart disease
The prevalence of neural tube defects is 7.0 per 10

Neural Tube Defect Prevalence 7.0 Per 10,000 in HIV-Exposed

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Prevalence of 7.0 per 10,000 HIV-exposed pregnancies similar to prevalence in general population
Children's hospitals participating in the Pediatric Cardiac Critical Care Consortium have improved cardiac surgery outcomes

Peds Cardiac Surgical Outcomes Improved in Consortium

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In-hospital mortality, major complications dropped for hospitals in Pediatric Cardiac Critical Care Consortium
The risk for mortality and end-stage kidney disease is high in children who undergo surgical repair for congenital heart disease compared with the general population

Surgery for Congenital Heart Disease Tied to Kidney Disease

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Higher risk for ESKD, death suggests closer monitoring needed, especially in first year after surgery
Adalimumab exposure in pregnancy does not increase the risk for birth defects

Risk for Birth Defects Not Increased With Adalimumab

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Risk for preterm delivery higher in women with RA, Crohn disease regardless of adalimumab exposure