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Home Tags Birth Defects: Misc.

Tag: Birth Defects: Misc.

Preeclampsia may increase risk of congenital heart defects

Preeclampsia Tied to Congenital Heart Defects

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But researchers stress the risk is still very low
Cerebral palsy is likely due to multiple prenatal factors

Birth Asphyxia Tied to Fewer Than 10% of Cerebral Palsy Cases

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Review suggests that causes other than asphyxia account for most cases in infants born at, near term
Women who follow a very healthy diet are much less likely than those who eat poorly to have a baby with tetralogy of Fallot or atrial septal defects

Healthier Diet Linked to Reduced Congenital Heart Defects

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Tied to reduced risks of tetralogy of Fallot and atrial septal defects
New research provides more evidence of a possible link between selective serotonin reuptake inhibitor antidepressant use early in pregnancy and a small increased risk of birth defects. The study appears online July 8 in The BMJ.

Another Study Shows Link Between SSRIs and Birth Defects

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But finding doesn't prove medications caused increased risk of birth defects
Curcumin appears to reduce high glucose-induced neural tube defect formation by blocking cellular stress and activation of caspases

Curcumin Reduces High Glucose-Induced NTDs in Mice Embryos

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Suppresses oxidative stress, blocks endoplasmic reticulum stress, abolishes caspase 3 and 8 cleavage
Evidence-based folate concentration guidelines for the prevention of neural tube defects have been developed by the World Health Organization

WHO Offers Evidence-Based Folate Concentration Guidelines

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For greatest decrease in neural tube defects, RBC folate concentrations should be >400 ng/mL
Implementation of a national screening program in the Netherlands increased the prenatal detection rate of congenital heart disease

National Prenatal Screening Program Increased CHD Detection

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Increase in prenatal detection rate to 59.7 percent, and 44.2 percent for isolated CHD
Neural tube defects have fallen 35 percent in the United States since mandatory folic acid fortification of enriched grain products was introduced in 1998; however

CDC: Neural Tube Defects Declining in the United States

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Still, not enough women are getting enough folic acid