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Functional genes in the upper airway microbiome may be tied to childhood asthma

Researchers ID Microbiome Genes Tied to Asthma

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Upper airway microbiota differs in children with asthma, asthma remission, and no asthma
Inhaled corticosteroids are not associated with increased odds of fracture in the pediatric asthma population

Inhaled Corticosteroids Not Linked to Fracture in Children

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Systemic, but not inhaled, corticosteroids associated with higher fracture risk in pediatric asthma patients
Promotion of prolonged and exclusive breastfeeding may reduce the risk of flexural dermatitis in adolescence but does not affect lung function or questionnaire-derived measures of asthma or atopic eczema

Extended Breastfeeding May Cut Later Flexural Dermatitis Risk

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But breastfeeding promotion not tied to measures of atopic eczema, asthma on questionnaire

American College of Allergy, Asthma and Immunology, Oct. 26-30

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The 2017 Annual Meeting of the American College of Allergy, Asthma & Immunology The annual meeting of the American College of...
Adults with work-related asthma are more likely that those with non-work-related asthma to have received pneumococcal vaccination

Pneumococcal Vaccine for Only Half With Work-Related Asthma

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54 percent of adults with work-related asthma, 35 percent with non-work-related asthma vaccinated
For patients with uncontrolled asthma despite treatment with long-acting beta-agonists and medium-to-high doses of inhaled glucocorticoids

Reduced Asthma Exacerbations Seen With Tezepelumab

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Reduction seen with three dose levels of tezepelumab regardless of blood eosinophil counts
Asthma is associated with subsequent development of inflammatory bowel disease

Asthma Tied to Later Inflammatory Bowel Disease

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Findings for Crohn's and early- or late-onset ulcerative colitis
In 2015

Global Disease Burden of COPD, Asthma Quantified

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More deaths due to COPD than asthma worldwide in 2015; increase in COPD deaths since 1990
Probiotic administration during the first six months of life does not reduce the incidence of eczema at 2 years of age or asthma at 5 years of age

Probiotics in Infancy Do Not Reduce Incidence of Eczema

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Probiotics in first six months of life do not reduce incidence of eczema at age 2, asthma at age 5
Maternal exposure to diesel exhaust particles during pregnancy may increase susceptibility to allergic asthma in more than one generation of offspring

Pollutant Exposure May Lead to Multi-Generational Asthma Risk

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Elevated susceptibility to allergic asthma persists into F2, and with lesser magnitude, into F3 mice