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Continuous and intermittent administration of β-lactam antibiotics are similarly efficacious for patients with severe sepsis

Outcomes Equal for Continuous, Intermittent β-Lactams in Sepsis

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No differences in ICU-free days, 90-day survival, organ failure-free days, bacteremia duration
For contacts of individuals with multidrug-resistant tuberculosis

Fluoroquinolones Halt Multidrug-Resistant-TB in Contacts

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FQN preventive therapy linked to health system savings and lower mortality versus no therapy
The antibiotic dicloxacillin may lessen the effects of vitamin K antagonists

Antibiotic May Reduce Anticoagulant Effect of Warfarin

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Doctors should closely monitor patients who have to take these drugs together, researcher says
Antibiotic use may increase the risk of juvenile idiopathic arthritis

Antibiotic Use Linked to Higher Odds of Juvenile Arthritis

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Risk greatest within a year of receiving antibiotics; increases with number of courses prescribed
For patients undergoing transrectal prostate biopsy

Targeted Prophylaxis Effective in Post-Prostate Biopsy Sepsis

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Targeted prophylaxis similarly effective to empirical prophylaxis after transrectal prostate biopsy
Macrolide-resistant Mycoplasma pneumoniae has a prevalence of 13.2 percent in a sample of M. pneumoniae-positive specimens from six locations in the United States

Macrolide-Resistant M. pneumoniae in All U.S. Regions

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Prevalence of 13.2 percent in sample of 91 M. pneumoniae-positive specimens from six locations
Many American parents still have misconceptions about when their children should receive antibiotics and what the medications do

Antibiotic Misconceptions Still Common Among Parents

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Those with Medicaid insurance tend to know less about the drugs, researchers find
An antibiotic stewardship program with pharmacist participation can promote improved antibiotic use and decrease costs in clean urological procedures

Antibiotic Stewardship Program Improves Antibiotic Use in China

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Program with pharmacist participation cuts antibiotic use and costs in clean urological procedures
Among hospitalized patients

High Doses of Antibiotic Ups Risk of Over-Anticoagulation

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High-dose amoxicillin/clavulanate combined with warfarin linked to increased risk of INR ≥4
Fluoroquinolone therapy for contacts of individuals with multi-drug resistant tuberculosis is associated with cost savings and reduced incidence of multi-drug resistant tuberculosis

Fluoroquinolone Preventive Therapy Deemed Beneficial in TB

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Health system savings, health benefits with therapy for contacts of patients with multi-drug resistant TB