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Antibiotic Noninferior to Ceftriaxone + Azithromycin for Gonorrhea

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Neither treatment group had bacterial persistence of urogenital Neisseria gonorrhoeae at test-of-cure

Guideline Adherence Suboptimal for Chlamydia, Gonorrhea Treatment

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14.0 percent of chlamydia cases and 38.7 percent of gonorrhea cases receive treatment with recommended antibiotic

Low-Dose Doxycycline Effective for Lymphocytic Scarring Alopecias

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Effectiveness with low-dose doxycycline as effective as with high doses, but with greater tolerability

Three All-Oral Shortened Regimens Noninferior for Rifampin-Resistant TB

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Noninferior efficacy seen for three all-oral regimens compared with standard therapy in intention-to-treat, per-protocol populations

Early-Life Infection Burden Linked to Risk for Later Infections

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Risk increased for later moderate-to-severe infections and systemic antibiotic treatments

DoxyPEP Tied to Decreases in Sexually Transmitted Infections

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Substantial declines seen in chlamydia and syphilis incidence after initiation

Antibiotic Use Not Linked to Incident Dementia, Cognitive Impairment

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No association seen for increased risks for dementia, cognitive impairment without dementia, accelerated cognitive decline

Sepsis Care Guided by Daily Procalcitonin Cuts Antibiotic Duration

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However, no difference seen for care guided by C-reactive protein measurement

Nonoperative Management Cost-Effective for Pediatric Appendectomy

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Compared with laparoscopic appendectomy, nonoperative management was also more effective

Many PCPs Prescribe Antibiotics for Pneumonia Even With Negative Chest X-Ray

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More than two-thirds of patients with negative chest X-ray results prescribed antibiotics