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Downregulation of miR-126 Augments DNA Damage Response

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Reduced miR-126 levels in lungs from mice exposed to cigarette smoke, smokers' lung epithelial cells
The Zika virus doesn't appear to be transmitted through saliva

Little Risk of Oropharyngeal Mucosal Transmission of Zika

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Research with monkeys suggests virus isn't transmitted through kissing, sharing eating utensils
Amyloid polypeptide deposits in the pancreas may lead scientists to a better understanding of type 2 diabetes

Diabetes Symptoms Appear to Spread Via Prion-Like Mechanism

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Injections in mice led to symptoms of the disease, researchers report
Galectin-1 (Gal-1)

Immunotherapy Efficacy Up With Gal-1/SIT Co-Administration

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Suppressed allergic responses in mouse intestine with Gal-1, allergen-specific immunotherapy
Maternal exposure to diesel exhaust particles during pregnancy may increase susceptibility to allergic asthma in more than one generation of offspring

Pollutant Exposure May Lead to Multi-Generational Asthma Risk

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Elevated susceptibility to allergic asthma persists into F2, and with lesser magnitude, into F3 mice
Animal research may have yielded a potential treatment for fetal alcohol spectrum disorder in children; the new report was published online July 18 in Molecular Psychiatry.

Animal Study Reveals Potential of Fetal Alcohol Damage Reversal

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Two common medications show promise in lab rats, researchers report
In farnesoid X receptor knockout mice

Western Diet Associated With Chronic Hepatic Inflammation

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Western diet-induced dysbiosis in FXR KO mice linked to persistent hepatic inflammation
Sildenafil-coated stents appear to cut a patient's odds for clots

Sildenafil-Coated Stent May Help Prevent Clots, Stenosis

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In animal study, sildenafil showed potential in reducing both restenosis and blood clot formation
The combination of extra virgin olive oil and ibuprofen at a therapeutic dose is superior to the two compounds used separately

Olive Oil, Ibuprofen May Have Synergistic Effects

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Synergistic analgesic, anti-pyretic, anti-inflammatory effects seen in animal model
An experimental study supports a TANK-binding kinase 1-dependent role for Lin28a in the hypothalamic ventromedial nucleus in glucose homeostasis. The study was published online May 26 in Diabetes.

Hypothalamic Lin28a Shows Role in Glucose Homeostasis

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Hypothalamic ventromedial Lin28a enhances glucose metabolism in diet-induced obesity in mice