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Dana Farber Cancer Center to Retract or Fix Dozens of Studies

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By Robin Foster HealthDay Reporter TUESDAY, Jan. 23, 2024 (HealthDay News) -- The prestigious Dana Farber Cancer Institute in Boston will retract six studies and...

Diabetes More Prevalent in Black Patients With Multiple Myeloma

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Diabetes linked to reduced overall survival, especially in Whites; in mouse model, progression of MM xenografts faster in mice with diabetes

Scientists Spot Clues to Why Omicron Infections Are Milder

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More than a dozen research groups have been observing the omicron variant in lab settings using animals this past month

Microneedle array delivery of trimeric coronavirus spike protein subunit vaccines seems promising for immunization against severe acute respiratory syndrome coronavirus 2 infection

Test Vaccine Elicits Strong Ab Response to SARS-CoV-2 in Mice

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Microneedle array-delivered S1 subunit vaccine elicits potent antigen-specific antibody response in mice
Obesity may cause a differential response to antiarrhythmic drugs used to suppress atrial fibrillation

Obesity Mediates Response to Antiarrhythmic Drugs in A-Fib

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Reduced response to sodium versus potassium channel blocker AADs seen in obese patients, mice
The eventual elimination of chemical testing on mammals was announced Tuesday by the U.S. Environmental Protection Agency.

EPA to Phase Out Chemical Testing on Mammals

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Agency plans 30 percent reduction in number of studies that require use of mammals by 2025
In a mouse model of moderate

Ciprofloxacin May Up Likelihood of Aortic Dissection, Rupture

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Increased susceptibility observed in mouse model of sporadic aortic aneurysm and dissection
An oral insulin formulation has been developed using choline and geranate ionic liquid

Oral Insulin Choline, Geranate Ionic Liquid Shows Promise

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Significant, sustained decrease in blood glucose levels with low insulin doses of 3 to 10 U/kg
Final guidance has been issued by the U.S. Food and Drug Administration to assist in the development of drugs for the prevention of inhalational anthrax for individuals who may have been exposed but who have not yet displayed related signs or symptoms.

FDA Issues Final Guidance on Inhalational Anthrax

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Final guidance designed to assist in development of drugs for prophylaxis of inhalational anthrax
An ingestible micro-bio-electronic device could be used for in situ biomolecular detection based on environmentally resilient biosensor bacteria and luminescence readout electronics

Ingestible Bio-Electronic Device Could Monitor GI Health

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Heme-sensitive probiotic biosensors demonstrate accurate diagnosis of GI bleeding in swine model